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Total results with these characteristics: 279

Disease: Rotavirus

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Rotavirus Vaccine Safety

This web page provides a thorough review of rotavirus vaccine safety, with a particular focus on monitoring for the possibility of intussusception after vaccination. It includes links to numerous technical resources with rotavirus vaccine safety …

Author: US Centers for Disease Control and Prevention

Rotavirus Vaccine—A Powerful Tool to Combat Deaths From Diarrhea

This editorial, published in The New England Journal of Medicine, comments on recent efficacy trials of rotavirus vaccine in South Africa and Malawi and a postmarketing study in Mexico. Based on the data, the author recommends the introduction …

Author: Santosham M

Publication date: 2010

Rotavirus Vaccines - WHO Position Paper

This article, published in Weekly Epidemiological Record, summarizes the World Health Organization's recommendations on rotavirus vaccines and related activities, including vaccine introduction, surveillance of rotavirus disease, and studies to …

Author: World Health Organization

Publication date: 2007

Rotavirus Vaccines: An Update - WHO Position Paper

This article, published in the Weekly Epidemiological Record, summarizes the World Health Organization's recommendations on rotavirus vaccines and related activities, including vaccine introduction, surveillance of rotavirus disease, and …

Author: World Health Organization

Publication date: 2009

Rotavirus Vaccines and Health Care Utilization for Diarrhea in the United States (2007–2011)

This article, published in Pediatrics, reports on a study that examined reductions in diarrhea-associated health care utilization after rotavirus vaccine implementation in the United States (US) in order to assess direct and indirect effectiveness …

Author: Leshem E, Moritz RE, Curns AT, et al.

Publication date: 2014

Rotavirus Vaccines for Children in Developing Countries

This supplemental issue of Vaccine summarizes data on the performance of rotavirus vaccines to help maximize their impact in developing countries and adds to the body of evidence demonstrating that rotavirus vaccines are a safe, proven, …

Author: Steele AD, Neuzil KM, Parashar UD, eds.

Publication date: 2012

Rotavirus Vaccines: Rapid Rollout is Saving Lives

This animated video and companion infographic highlight the progress made in reducing rotavirus disease burden due to the rapid introduction of rotavirus vaccines in more than 75 countries worldwide. They show that while great progress has been …

Author: PATH

Publication date: 2015

Rotavirus Vaccines: WHO Position Paper - January 2013

This article, published in the Weekly Epidemiological Record, reaffirms the World Health Organization's recommendation that rotavirus vaccines should be included in all national immunization programs, especially in countries with high death rates. …

Author: World Health Organization

Publication date: 2013

Rotavirus-Associated Hospitalization and Emergency Department Costs and Rotavirus Vaccine Program Impact

The New Vaccine Surveillance Network began conducting surveillance for the economic burden of rotavirus in three counties in the United States (Hamilton County, Ohio; Davidson County, Tennessee; and Monroe County, New York) in 2006 and continued …

Author: Kilgore A, Donauer S, Edwards KM, et al.

Publication date: 2013

Rotaviruses: Cause of Vaccine-Preventable Disease Yet Many Fundamental Questions Remain to Be Explored

This editorial, published in Current Opinion in Virology, details the molecular structure and pathogenesis of rotavirus and outlines important areas for further research of current rotavirus vaccines. These include the causes of decreased efficacy …

Author: Estes MK, Desselberger U

Publication date: 2012

Routine Laboratory Testing Data for Surveillance of Rotavirus Hospitalizations to Evaluate the Impact of Vaccination

Researchers used laboratory and hospital data of children admitted to two US hospitals with acute gastroenteritis to assess the need for routine rotavirus testing and determine disease burden. Findings confirmed the need for continued surveillance …

Author: Patel MM, Tate JE, Selvarangan R, et al.

Publication date: 2007

Safety and Efficacy of a Pentavalent Human-Bovine (WC3) Reassortant Rotavirus Vaccine

This study, published in The New England Journal of Medicine, evaluated the safety and efficacy of Merck’s rotavirus vaccine (RotaTeq®), with a focus on determining risk of intussusception.

Author: Vesikari T, Matson D, Dennehy P, et al.

Publication date: 2006

Safety and Efficacy of an Attenuated Vaccine Against Severe Rotavirus Gastroenteritis

This study, published in the New England Journal of Medicine, evaluated the safety and efficacy of GSK’s rotavirus vaccine (Rotarix®), with a focus on determining risk of intussusception.

Author: Ruiz-Palacios G, Pérez-Schael I, Velázquez F, et al.

Publication date: 2006

Safety and Immunogenicity of a Parenteral P2-VP8-P[8] Subunit Rotavirus Vaccine in Toddlers and Infants in South Africa: A Randomised, Double-Blind, Placebo-Controlled Trial

Low-income countries in Africa and Asia have the highest burden of rotavirus disease, but live oral rotavirus vaccines have shown reduced efficacy in these countries compared with high-income countries. This article, published in the Lancet …

Author: Groome MJ, Koen A, Fix A, et al.

Publication date: 2017

Safety and Immunogenicity of a Parenterally Administered Rotavirus VP8 Subunit Vaccine in Healthy Adults

This article, published in Vaccine, reports on a study to evaluate the safety and immunogenicity of a non-replicating rotavirus vaccine candidate. The authors found that the vaccine was well-tolerated in healthy adults and evoked promising immune …

Author: Fix AD, Harro C, McNeal M, et al.

Publication date: 2015

Safety of Vaccines Used for Routine Immunization of US Children: A Systematic Review

This article, published in Pediatrics, reviews the existing literature on the safety of routine vaccines recommended for children in the United States. The authors found evidence that some vaccines are associated with serious adverse events; …

Author: Maglione MA, Das L, Raaen L, et al.

Publication date: 2014

Safety, Tolerability, and Immunogenicity of Pentavalent Rotavirus Vaccine Manufactured by a Modified Process

This article, published in the Pediatric Infectious Disease Journal, describes the results of a Phase 3 study of a modified formulation of RotaTeq® (RV5) rotavirus vaccine that was developed to be stable at 37°C for 7 days and that has an …

Author: Martinón-Torres F, Dionne M, Greenberg D, et al.

Publication date: 2017

Saving Children's Lives From Deadly Rotavirus Diarrhea: PATH's Comprehensive Approach to Rotavirus Vaccines

This fact sheet highlights PATH’s work to address rotavirus, the leading cause of severe diarrheal disease. It includes general information about our efforts to increase access to and effectiveness of existing vaccines, as well as to develop new …

Author: PATH

Publication date: 2016

Software for National-Level Vaccine Cold Chain Equipment Management

The Cold Chain Equipment Manager (CCEM) is an inventory and planning tool that utilizes Microsoft Access–based software and analytic tools to help with data collection and analysis. Planning algorithms, data visualization, system modeling, and …

Author: University of Washington, PATH

Publication date: 2012

Stability of Live Attenuated Rotavirus Vaccine With Selected Preservatives and Primary Containers

This article, published in Vaccine, reports the results of a study to evaluate the feasibility of using preservatives to develop a liquid multi-dose formulation and primary packaging alternatives for orally delivered, liquid rotavirus vaccines. The …

Author: Lal M, Jarrahian C, Zhu C, et al.

Publication date: 2016

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