Published in Epidemiology and Infection, this article examines both population- and facility-based studies of ETEC infections and identifys a need for additional large, population-based studies combined with facility-based studies covering …

Published in Epidemiology and Infection, this article seeks to identify contemporary gaps in the understanding of the global epidemiology of shigellosis, through a review of the English-language scientific literature from 1984 to 2005, …

This article was published in the journal Vaccine. Enterotoxigenic Escherichia coli (ETEC) is the most common bacterial cause of diarrhoea in the world, annually affecting up to 400,000,000 children under 5 years of age living in developing …

This article, published in the New England Journal of Medicine, provides a description of bacterial diarrhea and evidence supporting various strategies to combat this problem. Also included are a list of pathogens that cause bacterial diarrhea and …

COTS is an e-book, funded by the US Agency for International Development, designed to export the clinical, scientific, and public health expertise on cholera and shigellosis from the International Centre for Diarrhoeal Disease Research, …

Published in Health Policy and Planning, this compares cost-of-illness (COI) with stated preference estimates of willingness-to-pay associated with shigellosis in a rural area of China to evaluate the economic benefits of disease …

This article, published in Value in Health, discusses a study to develop a cost function model to estimate the public treatment cost of shigellosis patients in Thailand. The study was an incidence-based cost-of-illness …

This fact sheet highlights PATH's work to develop safe, effective, and affordable vaccines against Shigella and enterotoxigenic Escherichia coli, two of the leading bacterial causes of diarrheal disease.

This presentation from the Vaccines for Enteric Diseases conference provides results from a clinical trial that found the human challenge model currently being used to test vaccines against enterotoxigenic Escherichia coli (ETEC) is utilizing a …

Diarrheal Disease: Solutions to Defeat a Global Killer presents scientific evidence to support strategies to scale up use of interventions, including safe water, improved sanitation and hygiene, breastfeeding and optimal complementary feeding, …

This joint report from the World Health Organization and the United Nations Children's Fund (UNICEF) focuses attention on the prevention and management of diarrheal diseases. It examines the latest available information on the burden of childhood …

Published in Infection and Immunity, a cohort of 321 children were followed from birth up to two years to determine the incidence of enterotoxigenic Escherichia coli (ETEC) in Bangladesh. Children with ETEC diarrhea were underweight and stunted …

This website, managed by PATH and UNICEF, provides comprehensive resources on diarrheal disease treatment interventions, including low-osmolarity oral rehydration solution, zinc treatment, and rotavirus vaccines. Traditional interventions such …

This web page provides information in enteric diseases, including NIAID-supported research, meeting summaries, news releases, and resources for researchers.

Published in the journal Vaccine, this article discusses the importance of creating reliable, long-term demand for the next generation of enteric vaccines, including new rotavirus, Shigella, and ETEC vaccines and priorities for achieving this …

Enteric infections, with or without overt diarrhea, have profound effects on intestinal absorption, nutrition, and childhood development as well as on global mortality. Oral rehydration therapy has reduced the number of deaths from dehydration …

From the Weekly Epidemiological Record, this report is from an international consultative meeting on ETEC to examine the most recent epidemiological data from the field, identify gaps in the laboratory methods for strain …

This web page provides information on ETEC disease burden and vaccine development, as well as useful links.

This web page provides information on ETEC, its transmission, prevention of the disease, and more.

This article was published in Clinical Microbiology Reviews. ETEC is an underrecognized but extremely important cause of diarrhea in the developing world where there is inadequate clean water and poor sanitation. It is the most frequent bacterial …

WaterAid's report Fatal Neglect: How Health Systems Are Failing to Comprehensively Address Child Mortality shows how the aid system is not responding to the causes of child mortality in a targeted manner. The international health agenda is failing …

This protocol provides a generic outline for a study to assess local Shigella disease burden and describes the main procedures involved. However, it will need to be adapted to local settings, and details of field work and operational …

This fact sheet describes PATH's work in vaccines and immunization.

Published in the Journal of Clinical Microbiology, this article examins the burden of diarrheal disease due to enterotoxigenic E. coli among rural Egyptian infants and young children, whic has an incidence of 1.5 episodes per child per …

This briefing paper provides an overview of the tools and interventions involved with an integrated approach to diarrheal disease control, including vaccines, oral rehydration therapy, breastfeeding, and zinc treatment. The document also advocates …