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Total results with these characteristics: 212

Disease: Pneumococcus

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Inferior Quantitative and Qualitative Immune Responses to Pneumococcal Conjugate Vaccine in Infants With Nasopharyngeal Colonization by Streptococcus pneumoniae During the Primary Series of Immunization

This study, published in Vaccine, corroborates previous hypotheses that infant nasopharyngeal colonization at any stage before completing the primary series of pneumococcal conjugate vaccine (PCV) was associated with inferior quantitative and …

Author: Madhi SA, Violari A, Klugman KP, et al.

Publication date: 2011

Integrating Diarrheal Disease and Pneumonia Control

This fact sheet describes PATH's integrated approach to tackling diarrheal disease and pneumonia, two of the leading killers of young children. This approach emphasizes overlapping protection, the scale-up of proven methods, and the development of …

Author: PATH

Publication date: 2013

Introducing New Vaccines Into Developing Countries: Obstacles, Opportunities, and Complexities

This commentary, published in Nature Medicine, reviews current trends that may affect whether the most promising of the 350 vaccine candidates under development will eventually be used in programs for the poor in developing countries. It also …

Author: Clemens J, Jodar L

Publication date: 2005

Invasive Pneumococcal Disease in Children: Geographic and Temporal Variations in Incidence and Serotype Distribution

Published in the European Journal of Pediatrics, this study examined published studies from the United States, Europe, and Latin America to better understand geographic and temporal variability in the epidemiology of invasive pneumococcal disease …

Author: Hausdorff WP

Publication date: 2002

Is the Pneumococcal Vaccine Advance Market Commitment Motivating Innovation and Increasing Manufacturing Capacity? Some Preliminary Answers

This article, published in Vaccine, provides preliminary evidence on the potential outcome of the pneumococcal vaccine Advance Market Commitment, with a focus on its impact on innovation in emerging vaccine manufacturers in low-resource countries. …

Author: Plahte J

Publication date: 2012

Issues and Challenges in the Development of Pneumococcal Protein Vaccines

In view of the increasing licensure and use of pneumococcal conjugate vaccines, the relatively high cost, and growing issues with serotype emergence, there is a need to re-evaluate the role of pneumococcal protein vaccines (PPVs) and pathways to …

Author: Ginsburg AS, Nahm MH, Khambaty FM, Alderson MR

Publication date: 2012

Joint Vaccine Education Resource Center

This website provides resources in the field of immunization, including an extensive selection of peer-reviewed articles from the literature as well as links to valuable resources for scientists, clinicians, and patients focused on the most commonly …

Author: American Journal of Preventative Medicine; Vaccine

The Kinetics and Phenotype of the Human B-cell Response Following Immunization with a Heptavalent Pneumococcal CRM Conjugate Vaccine

Published in the journal Immunology, this study aimed to establish the kinetics and phenotype of B-cell subpopulations responding to booster immunization with a heptavalent pneumococcal conjugate vaccine (Pnc7), which is to be introduced into the …

Author: Clutterbuck EA, Salt P, Oh S, et al.

Publication date: 2006

Kinetics of the Immune Response Following Pneumococcal PD Conjugate Vaccination

Primary vaccination with pneumococcal protein D conjugate vaccine in the first year of life induced clear ELISA and OPA responses, which varied considerably for the different serotypes. Antibody levels declined following primary vaccination but were …

Author: Schuerman L, Prymula R, Chrobok V, Dieussaert I, Poolman J

Publication date: 2007

Laboratory-Based Diagnosis of Pneumococcal Pneumonia: State of the Art and Unmet Needs

This article, published in Clinical Microbiology and Infection, summarizes a meeting organized by PATH and Fondation Mérieux from October 18 to 20, 2009 in Les Pensiéres, France, during which participants evaluated current pneumococcal diagnostics …

Author: Vernet G, Saha S, Satzke C, et al.

Publication date: 2011

Landscape Analysis: Trends in Vaccine Availability and Novel Vaccine Delivery Technologies: 2008–2025

This landscape analysis identifies trends in the availability of vaccines and novel vaccine delivery technologies that are and will be of relevance to low- and middle-income countries from the present through 2025.

Author: PATH, World Health Organization

Publication date: 2008

Making New Vaccines Affordable: A Comparison of Financing Processes Used to Develop and Deploy New Meningococcal and Pneumococcal Conjugate Vaccines

Two innovative mechanisms have been used to accelerate the development of low-price supply lines for conjugate vaccines. The Meningitis Vaccine Project is a so-called push mechanism that facilitated technology transfer to an Indian company to …

Author: Hargreaves JR, Greenwood B, Clift C, et al.

Publication date: 2011

Maternal Immunisation in Developing Countries

This article, published in Vaccine, discusses the benefits and challenges of implementing maternal immunization as a method of preventing infections in the developing world. Specifically, the article discusses the high incidence of pneumococcal …

Author: Greenwood B

Publication date: 2003

Maternal Immunization: Country Priorities and Market Requirements

Maternal immunization is an approach of vaccinating during pregnancy to enhance immunity for both mother and baby. This report provides insight into country priorities for maternal immunization and characterizes the market for adult immunizations in …

Author: PATH

Publication date: 2015

Measuring Impact of Streptococcus pneumoniae and Haemophilus influenzae type b Conjugate Vaccination

This manual describes approaches to measuring pneumococcal and Haemophilus influenzae type b conjugate vaccine impact on disease incidence and provides a framework for determining the best methodology in a specific country setting. It details a …

Author: World Health Organization

Publication date: 2012

Meningococcal Conjugate Vaccines

This article, published in Expert Opinion on Pharmacotherapy, reviews the conjugate meningococcal vaccines currently available and under development and their potential for disease prevention. The article also includes a discussion of the successful …

Author: Zimmer SM, Stephens DS

Publication date: 2004

Merck Manual: Pneumococcal Infections

Merck’s website offers information about pneumococcal pneumonia.

Author: Merck

Molecular Typing of the Pneumococcus and its Application in Epidemiology in Sub-Saharan Africa

This article, published in Frontiers in Cellular and Infection Microbiology, discusses molecular typing of the pneumococcus and what is known about epidemiology of the organism in sub-Saharan Africa based on the various typing methods.

Author: Donkor ES

Publication date: 2013

Monitoring Visualization Tool for the Global Action Plan for Pneumonia and Diarrhoea (GAPPD)

This data visualization tool enables users to monitor progress against GAPPD targets for 2025/2030/2040, as well as the progress made by 136 low- and middle-income countries in averting childhood diarrhea and pneumonia deaths. The data are also …

Author: World Health Organization

Moving the Needle

This quarterly e-newsletter provides updates from PATH’s Center for Vaccine Innovation and Access on its vaccine development efforts, as well as related supporting work, such as developing human challenge models, building capacity of …

Author: PATH

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