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Laboratory Strengthening: Building Laboratory Capacity to Promote Universal Access to Quality Diagnosis and Expand Services for Drug-Resistant TB in India

This project brief outlines PATH’s work in strengthening national laboratories in India to correctly diagnose tuberculosis (TB), including multidrug-resistant tuberculosis (MDR-TB). In collaboration with FIND, the World Health Organization, and other partners, PATH provided intense technical assistance to India's Revised National TB Control Program to introduce new diagnostic technologies into Indian laboratories, improve biosafety and infrastructure, build nationwide laboratory networks, and strengthen quality assurance. This work was made possible through support from the United States Agency for International Development.

Publication date: May 2014

Region: Asia

Part of series: Tuberculosis activities in India

Magnesium Sulfate Dilution Bottle

Part of the Technology Updates series, this fact sheet describes PATH's work in adapting the concept of a dilution bottle to simplify the process of magnesium sulfate administration for the treatment of preeclampsia and eclampsia. A dilution bottle bottle can facilitate the safe calculation of recommended doses by obviating the need to remember complex equations for dilution.

Publication date: May 2014

Region: Global

Part of series: Technology Updates

Mobile Application for Dosing and Dilution of Magnesium Sulfate

Part of the Technology Updates series, this fact sheet describes PATH’s work in collaboration with the University of Washington to develop a mobile application for magnesium sulfate administration for the treatment of preeclampsia and eclampsia. The application includes a dosing calculator and a detailed checklist based on World Health Organization protocol and is designed specifically to address the challenges of correctly calculating the dosage.

Publication date: May 2014

Region: Global

Part of series: Technology Updates

Preventing the Spread of TB: Improving Infection Prevention and Control in India’s Health Facilities

This project brief describes one aspect of PATH’s contributions to tuberculosis (TB) control in India. With the support of the United States Agency for International Development, PATH worked with India’s Revised National TB Control Program to implement new national guidelines on airborne infection control in India. Work included developing education materials for health workers and their patients, convening experience-sharing workshops for national TB program staff, and training local engineers and architects to design effective infection-control measures within health facilities.

Publication date: May 2014

Region: Asia

Part of series: Tuberculosis activities in India

Public-Private Mix for TB Control: Indian Chemists Join National Efforts to Find and Treat More Cases of TB

This project brief describes PATH’s contributions to developing public-private mix (PPM) approaches to TB control in India. With support from the United States Agency for International Development, PATH supported a PPM pilot project in Andhra Pradesh that aimed to train private chemists in identifying presumed TB cases and referring them to government diagnosis centers, promoting community awareness of TB prevention, and reducing the sale of TB drugs to persons without a prescription. This project provided valuable lessons and insights into applying PPM strategies to future TB control projects in India and elsewhere.

Publication date: May 2014

Region: Asia

Part of series: Tuberculosis activities in India

Rectal Delivery of Magnesium Sulfate

Part of the Technology Updates series, this fact sheet describes PATH's work to develop a rectally administered magnesium sulfate (MgSO4) formulation that could simplify delivery and improve access to MgSO4 treatment in low-resource settings.

Publication date: May 2014

Region: Global

Part of series: Technology Updates

Rotavirus Disease and Vaccines in Eritrea

This fact sheet provides an overview of rotavirus disease and vaccines in Eritrea. It includes information about the tremendous burden of rotavirus diarrhea in Eritrean children, rotavirus diarrhea treatment and prevention strategies, and the effectiveness of rotavirus vaccines.

Publication date: May 2014

Region: Global

Part of series: Rotavirus disease and vaccines fact sheets

Rotavirus Disease and Vaccines in Niger

This fact sheet provides an overview of rotavirus disease and vaccines in Niger. It includes information about the tremendous burden of rotavirus diarrhea in Nigerien children, rotavirus diarrhea treatment and prevention strategies, and the effectiveness of rotavirus vaccines.

Publication date: May 2014

Region: Africa

Part of series: Rotavirus disease and vaccines fact sheets

SILCS Launches in Early Markets

The SILCS diaphragm is a single-size contraceptive barrier designed to fit a broad range of women. This document describes product features and the steps that PATH and our commercialization partner, Kessel Marketing & Vertriebs GmbH, are taking as we build toward the introduction of SILCS in low-resource settings.

Publication date: May 2014

Region: Global

Supporting Effective Management of Preeclampsia/Eclampsia: Mobile Application for Dosing and Dilution of Magnesium Sulfate

Severe preeclampsia and eclampsia (PE/E) are among the leading causes of maternal death and disability worldwide. Magnesium sulfate is the treatment recommended by the World Health Organization, but it remains underutilized due to difficult administration. PATH designed a mobile application for dosing and dilution of magnesium sulfate to address the challenges of correctly calculating magnesium sulfate dosage given multiple concentrations and a complex dosing regimen.

Publication date: May 2014

Region: Global

Tackling TB and HIV Co-infection in Tanzania: Results of an Innovative Model Launched in TB Clinics in Six Regions

This project brief showcases PATH's contributions to tuberculosis (TB) and HIV service integration in Tanzania. This work was made possible through generous funding from the United States Agency for International Development. For a related brief on pediatric TB in Tanzania, see Finding and Treating Tuberculosis in Children.

Publication date: May 2014

Region: Africa

Target Product Profile: HIV Self-Test Version 4.1: A White Paper on the Evaluation of Current HIV Rapid Tests and Development of Core Specifications for Next-Generation HIV Tests

This annotated target product profile (TPP) describes the desired characteristics of an HIV self-test and is a result of a review of currently available literature, interviews with key informants/stakeholders, laboratory-generated data on the performance of rapid tests, and early usability studies in Kenya, Malawi, and South Africa. The purpose of the TPP is to provide a common foundation for the development of HIV self-tests that contains sufficient detail to allow device developers and key stakeholders to understand the characteristics a test must have to be successful.

Author: Peck RB, Lim JM, Wellhausen JD, Lee AM, Valdez MM

Publication date: May 2014

Region: Global

Accelerating Malaria Elimination in Africa: PATH Partners With Malaria-Endemic Countries, the Private Sector, and the Global Community in the Quest for a Malaria-Free World

This fact sheet provides an overview of the work of PATH's Malaria Control and Elimination Partnership in Africa (MACEPA) to develop and document approaches for reducing malaria illnesses and deaths, with the long-term goal of malaria elimination.

Publication date: April 2014

Region: Africa

The Arise Program: Enhancing HIV Prevention Programs for At-Risk Populations

With funding from the Canadian International Development Agency, PATH is working to address the information gap on how to best tailor and scale up proven HIV prevention strategies among at-risk populations through cost-effective interventions in India, Senegal, Uganda, Zambia, and Zimbabwe.

Publication date: April 2014

Region: Global

Cervical Cancer Action: 2007 to 2014 . . . and Beyond

Cervical Cancer Action is a global partnership chaired by PATH and aimed at reducing cervical cancer in high-burden, low-income countries. Seven years after its founding and eight years after human papillomavirus vaccines first became available, Cervical Cancer Action offers this snapshot of its accomplishments to date and its vision of the work ahead.

Publication date: April 2014

Region: Global

Child Health in Tanzania: Identifying Policy Pathways to Help Prevent Child Deaths From Pneumonia and Diarrhea

This brief provides policy recommendations to help Tanzania reduce the impacts of pneumonia and diarrhea and ensure all children have the chance to lead healthy lives.

Publication date: April 2014

Region: Africa

Cold Chain Equipment Inventories

Part of the Technology Updates series, this fact sheet describes PATH and our partners’ work to validate a new web-based cold chain equipment inventory (CCEI) tool, which is a module of the DHIS2 open-source software platform. This tool will provide opportunities for countries to integrate CCEI data into their national health management information systems.

Publication date: April 2014

Region: Global

Part of series: Technology Updates

Fighting Malaria Today and Tomorrow: PATH Works With Developing Countries to Achieve a Malaria-Free World

This fact sheet describes PATH's work to eliminate malaria, including expanding the use of lifesaving tools, identifying and developing better diagnostics and drugs, devising new strategies for malaria control, and accelerating the development of malaria vaccines.

Publication date: April 2014

Region: Global

Part of series: Areas of focus fact sheets

Low-Cost Lung Support Models for Newborns

Part of the Technology Updates series, this fact sheet describes PATH's work on low-cost respiratory support devices for newborns.

Publication date: April 2014

Region: Global

Part of series: Technology Updates

Oral Delivery Technologies

Part of the Technology Updates series, this fact sheet describes PATH's approach to technologies for oral delivery of vaccines.

Publication date: April 2014

Region: Global

Part of series: Technology Updates

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