This document identifies key steps and information relevant to the development and implementation of a national procurement policy on safe-injection equipment. The intention is to increase patient and health worker safety, and especially to avoid medical transmission of bloodborne infections such as HIV, hepatitis B, and hepatitis C.

Publication date: April 2010

Region: Global

This report from the vaccine technologies team at PATH presents results from an economic model that calculates the costs involved in delivering IPV vaccine in Indian immunization clinics according to three strategies: (1) intradermal delivery of reduced volumes of vaccine per dose, (2) use of adjuvants to allow a reduced IPV antigen content per dose, and (3) reduction of the number of doses per IPV immunization schedule. The strategies include delivery by standard technique and with alternative delivery devices.

Author: Hickling J, Jones R, Nundi N, Zehrung D

Publication date: April 2010

Region: Global

This job aid was developed to support training of small-scale incinerator operators and provides key message about how to perform regular maintenance. Regular maintenance is critical to ensuring the incinerator functions optimally for the projected life of the unit.

Publication date: April 2010

Region: Global

This job aid was developed to support training of small-scale incinerator operators and summarizes safe and effective operation. Key steps are outlined, including preheating and optimal loading instructions. By following these steps, incinerator operators can help ensure the unit operates optimally, reaching desired temperatures and ensuring waste is safely treated.

Publication date: April 2010

Region: Global

As part of project Optimize, a five-year human papillomavirus (HPV) vaccine demonstration project is under way in Uganda and three other countries to demonstrate how existing health systems can be adapted to successfully provide HPV vaccine to young adolescent girls. HPV vaccine is a strong candidate for storage and transport in a controlled temperature chain at temperatures higher than the standard 2º to 8ºC cold chain storage.

Author: Robertson J, Mugisha E, Kumakech E, LaMontagne D, Janmohamed A, Kristensen D, Seruyange R, Bamwine J, Ssekito G, Newland S

Publication date: April 2010

Region: Global

PATH has demonstrated the use of CaO for heat and a proprietary engineered phase change material (EPCM) to maintain an assay mixture within a narrow temperature range suitable for isothermal amplification. We are currently working to develop, integrate, and validate components of this NAAT kit. Presented at: AACC 42nd Annual Oak Ridge Conference, April 22, 2010; San Jose, CA.

Author: LaBarre P, Beddoe A, Gerlach J, et al

Publication date: April 2010

Region: Global

The PATH-Lemos Chagas rapid test has great potential as a highly sensitive diagnostic test for Chagas disease, suitable for use at the point-of-care.  Presented at: AACC 42nd Annual Oak Ridge Conference, April 22, 2010; San Jose, CA.

Author: Barfield CA, Barney RS, Crudder CH, et al

Publication date: April 2010

Region: Global

The pro-viral DNA capture card maintains the fundamental value provided by dried blood spots (ease of collection and transport from remote settings) while reducing the costs and time of performing pediatric HIV testing in the laboratory. Presented at: AACC 42nd Annual Oak Ridge Conference, April 22, 2010; San Jose, CA.

Author: Stevens DS, Barfield CA, Emery S, Overbaugh J, Gerlach J

Publication date: April 2010

Region: Global

This guidebook captures lessons learned by PATH over the course of the Making Medical Injections Safer project, in both Centers for Disease Control and USAID countries, on selecting, procuring, and installing a small-scale incinerator for health care waste management.

Publication date: March 2010

Region: Global

Project Optimize is collaborating with the Vietnamese National Institute of Hygiene and Epidemiology on a series of activities designed to assess the opportunities and needs for strengthening the immunization system in Vietnam. This document reports the results of assessments of the vaccine supply chain in Vietnam, completed in March 2010.

Publication date: March 2010

Region: Asia

The purpose of this cost analysis study conducted at six health facilites was to determine the costs of replacing the existing delivery method with oxytocin in Uniject® for the prevention of postpartum hemorrhage. This study complements a larger study on acceptability and feasibility, Pilot Introduction of Oxytocin in Uniject® During Active Management of the Third Stage of Labor (AMTSL) at the Institutional Level in Guatemala.

Publication date: March 2010

Region: Latin America

This report shares the results of a pilot introduction of oxytocin in the Uniject® device for use with active management of the third stage of labor that was conducted at the institutional level in Guatemala in 2009. Results include details on the feasibility of introducing oxytocin in Uniject in this context as well as the acceptability of this technology among health care providers and facility managers. The cost analysis can be found here.

Publication date: March 2010

Region: Latin America

This document provides practical illustrations on how to use key global resources related to the procurement of safe-injection equipment. It is intended for use by country decision-makers responsible for selecting and procuring good-quality safe-injection equipment.

Publication date: March 2010

Region: Global

This brief provides a description of PATH's work in South Africa. Projects focus on advancing health technologies for mothers and children, preventing mother-to-child transmission of HIV, caring for caregivers of orphans and vulnerable children, advocating for sound microbicides research in Africa, supporting midwives who work on HIV and AIDS, and strengthening tuberculosis infection prevention and control.

Publication date: February 2010

Region: Africa

This document describes PATH's Maternal and Child Health Technology Initiative and its work to reduce maternal mortality in South Africa's KwaZulu Natal Province.

Publication date: February 2010

Region: Africa

This is part of a series of project briefs discussing the activities, research findings, and field experiences of PATH’s Safe Water Project.

Publication date: February 2010

Region: Global

Part of series: Safe water briefs

This document provides guidelines for implementing a procurement policy for safe injection and brings together issues that countries should consider when developing and implementing the procurement aspect of a national injection safety policy. The document points out issues to consider in transitioning from policy to implementation, regulatory factors, public-sector considerations, and the need to sensitize private-sector manufacturers. It also includes a landscape of manufacturers of safe injection equipment.

Publication date: January 2010

Region: Global

This document provides specifications for personal protective equipment for medical waste handlers and incinerator operators. It is intended to help with the selection and purchase of locally available equipment and can be adapted to local policies and product availability.

Publication date: January 2010

Region: Global

This report, the first annual policy report of the Global Health Technologies Coalition, makes recommendations for Congress and the Obama Administration to ensure that the United States maximizes its investment in global health and continues as a leader in global health research and development. The report makes recommendations in three areas: public financing, regulatory pathways, and incentives and innovative financing.

Publication date: 2010

Region: North America and Europe

Part of series: GHTC's annual policy reports

In the field of safe injection, PATH has served for more than 20 years in a global leadership role, championing improved approaches to injection safety for the developing world. This document summarizes PATH's safe injection work over the past 10 years and includes information related to the development of policies and standards for injection safety as well as a list of safe injection technology evaluations conducted by PATH. This document also contains a list of PATH reports, peer-reviewed journal articles, and technical resources published over the past ten years.

Publication date: December 2009

Region: Global