PATH’s global community of donors and partners stepped up to support health equity through the Reach Campaign, our first major fundraising initiative. This report shares the final campaign results, including what PATH donors have made possible through their support.

Publication date: February 2018

Region: Global

Part of series: Reports to contributors

Part of the Technology Updates series, this fact sheet describes PATH's work on technologies to make the reconstitution of critical vaccines simpler, safer, and more economical. Streamlined reconstitution processes also help reduce medical wastage.

Publication date: February 2018

Region: Global

Part of series: Technology Updates

Advocacy is an effective method to achieve global health goals by ensuring that necessary resources, policies, and political will are available to support important programs. These resources help new and experienced advocates assess policy advocacy options, plan goals and activities, and develop a comprehensive strategy for advocacy impact. For more information, please visit: http://sites.path.org/advocacyandpolicy/how-we-do-it/strengthen-advocacy-capacity/.

Publication date: February 2018

Region: Africa, Asia, Global

This publication captures the milestones and process used by PATH in its role as Market Manager for the introduction and scale of 7.1% chlorhexidine for umbilical cord care globally over the last ten years.

Publication date: January 2018

Region: Global

This document was created to support ministry of health and nongovernmental partners as they develop strategies to introduce and scale up subcutaneous DMPA (DMPA-SC, brand name Sayana® Press) to increase contraceptive options and access. Available in English and French, the publication provides practical guidance based on results, evidence, and learning from the pilot introductions of Sayana Press in four countries in Africa. For more information, visit PATH's Reproductive Health Global Program website.

Publication date: January 2018

Region: Global

Subcutaneous DMPA (DMPA-SC, Sayana® Press) is a new, easy-to-use injectable contraceptive that is ideally suited for remote access and even self-injection. This brief provides an overview of PATH’s research studies assessing the feasibility and acceptability of self-injection in Uganda and Senegal. For more information, please visit our Reproductive Health Global Program website.

Publication date: January 2018

Region: Global

Part of series: Sayana Press (DMPA-SC in Uniject) introduction and research fact sheets

Subcutaneous DMPA is an innovative injectable contraceptive that can dramatically expand access and choice for women. A new initiative led by PATH and John Snow Inc., the Subcutaneous DMPA Access Collaborative is working with ministries of health and partners across sectors to strengthen scale-up and build toward a robust global market for the product. For more information, visit http://sites.path.org/rh/?p=292.

Publication date: January 2018

Region: Global

This case study examines the use of advocacy for increased misoprostol access in Nigeria, specifically the market-based approach taken by PATH and the Generation Initiative for Women and Youth network to design an initiative for increasing public-sector use of the drug.

Publication date: December 2017

Region: Africa, Global

This case study examines the use of advocacy to reduce newborn infections in Bangladesh, specifically the market advocacy efforts by PATH and the Bangladesh Pediatric Association to engage public and private stakeholders to understand the importance of 7.1 percent chlorhexidine digluconate use.

Publication date: December 2017

Region: Asia, Global

This fact sheet describes PATH’s work to increase access to oxygen therapy for the treatment of life-threatening pneumonia and hypoxemia in newborns and children. Facilitating inclusion of expanded uses of oxygen on the World Health Organization’s Essential Medicines List, as well as the inclusion of oxygen technologies and pulse oximetry in global commodity lists and treatment guidelines, are essential for reducing child mortality.

Publication date: December 2017

Region: Global

Part of series: Oxygen technologies

In low-transmission settings, submicroscopic quantities of Plasmodium falciparum are undetectable by current rapid diagnostic tests and ELISAs. Detection of this reservoir is essential, and we need a highly sensitive laboratory reference assay to confirm these infections. This study aimed to characterize the analytical and diagnostic performance of Alere’s high-sensitivity test.

Author: Das S, Jang I, Barney B, Peck R, Rek J, Arinaitwe E, Adrama H, Murphy M, Imwong M, Ling C, Proux S, Haohankhunnatham W, Seilie A, Hanron A, Daza G, Chang M, Nakamura T, Kalnoky M, LaBarre P, Murphy S, Nosten F, Greenhouse B, Domingo G

Publication date: November 2017

Region: Global

Part of series: ASTMH posters

This study assessed the technical and programmatic feasibility of a microarray patch for sustained, intradermal delivery of primaquine to treat P. vivax malaria. The team conducted an analysis to assess the potential for using microarray patches for delivery of primaquine and to inform the development of target product profile characteristics.

Author: McGray S, Unadkat D, Rein-Weston A, Jarrahian C, Donnelly RF, Zehrung D

Publication date: November 2017

Region: Global

Part of series: ASTMH posters

Efforts to reduce transmission and eliminate malaria require an understanding of biology and transmission. A model to induce gametocytes to understand their dynamics and evaluate transmission-blocking interventions is currently unavailable. Here, we explore the use of the Controlled Human Malaria Infection model to induce gametocyte carriage with antimalarial drug regimens.

Author: Reuling I, van de Schans L, Coffeng L, Lanke K, Graumans W, van Gemert G, Teelen K, Siebelink-Stoter R, van de Vegte-Bolmer M, de Mast Q, van der Ven A, Ivinson K, Hermsen C, de Vlas S, Bradley J, Collins K, Ockenhouse C, McCarthy J, Bousema T,. Sauerwein

Publication date: November 2017

Region: Global

Part of series: ASTMH posters

Environmental enteric dysfunction (EED) is associated with serious risks for children in low-resource settings. We currently need a tool to quantitate EED biomarkers to increase the efficiency of EED screening before clinical trial enrollment. This study worked to develop an assay to detect and quantify EED biomarkers in human specimens

Author: Arndt M, Cantera J, Choy R, Tyler A, Lyman C, Boyle D

Publication date: November 2017

Region: Global

Part of series: ASTMH posters

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory infections (ALRI) in infants and children across the globe. This fact sheet summarizes the latest RSV ALRI burden estimates at global, regional, and national scales.

Publication date: November 2017

Region: Global

PATH’s Scale-Up project works to expand the use of human papillomavirus (HPV) testing for cervical cancer prevention. Based on PATH’s experience implementing the careHPV™ test in Central America, this manual, available in Spanish and English, provides guidance for organizing a quality assurance program to screening programs adopting the careHPV test.

Publication date: November 2017

Region: Latin America, Global

Asymptomatic malaria infection in endemic areas presents new challenges, as the asymptomatic individuals constituting the human parasite reservoirs contribute to transmission. To achieve elimination, asymptomatic and submicroscopic reservoirs must be identified and treated. Here we sought to develop a highly sensitive tool to detect P. falciparum and P. vivax infection.

Author: Jang I, Tyler A, Lyman C, Barney B, Rashid A, Kahn M, Rist M, Kalnoky M, Das S, Peck R, Seilie A, Hanron A, Daza G, Chang M, Murphy S, McCarthy J, Domingo J

Publication date: November 2017

Region: Global

Part of series: ASTMH posters

The primer provides the data, messages, and resources to help understand the planning, policies, and technologies involved in oxygen delivery scale-up. The materials are useful to anyone who wants to learn about scaling up access to oxygen and integrating oxygen delivery across national and subnational policies, programs, and health budgets.

Author: Delarosa J, Pantjushenko E, Keith B, Ambler G, Lawrence C, Hayes, J

Publication date: November 2017

Region: Global

Part of series: Oxygen technologies

This policy brief brings attention to current global policies that support the provision of human milk, including donor human milk from milk banks, and encourages policymakers to take actions that will increase access to donor human milk for sick and vulnerable newborns.

Publication date: November 2017

Region: Global

Currently, the only drugs that radically cure Plasmodium vivax malaria are 8-aminoquinoline–based drugs, which can cause hemolysis in G6PD-deficient patients. Therefore, determination of G6PD level is critical before treatment. This study evaluated tests for G6PD deficiency, including validating the correlation of quantitative reference assays, and establishing recombinant G6PD controls.

Author: Pal S, LaRue N, Hrutkay S, Barney B, Kahn M, Bansil P, Kalnoky M, LeaderT, Domingo G

Publication date: November 2017

Region: Global

Part of series: ASTMH posters