This set of fact sheets details technical activities of PATH's Japanese encephalitis project, with an aim to inform future efforts and programs. The fact sheets were developed as a supplement to PATH's Japanese Encephalitis Project: Collaboration and Commitment to Protect Asia's Children. Topics covered include surveillance of disease burden and disability, cost-effectiveness analysis, diagnostics, advocacy, vaccine development, and vaccine introduction.

Publication date: December 2009

Region: Global

The purpose of this project Optimize survey was to obtain input from stakeholders within the Expanded Programme on Immunization in Vietnam about issues and perceptions related to the storage, distribution, and delivery of the current and potential options for human papillomavirus vaccine presentation and packaging.

Publication date: December 2009

Region: Asia

PATH’s Safe Water Project is exploring the effectiveness of commercial strategies for providing household water treatment and storage products to low-income consumers in Cambodia and other developing countries. This project brief summarizes the results of three studies—a consumer study, a product scan, and an analysis of distribution channels—conducted from April to December 2008 to inform the development and implementation of a safe water pilot project in Cambodia.

Author: Kols A

Publication date: December 2009

Region: Asia

A description of a viral RNA extraction and stabilization platform. Presented at: The 5th Annual World Healthcare Innovation and Technology Congress (WHIT v.5.0), November 8, 2009; Alexandria, VA.

Author: Beddoe AG, Hubbard L, Stevens D, et al

Publication date: November 2009

Region: Global

A report on work aimed to determine the main bacterial enteric pathogens causing diarrhea in children treated in emergency rooms in Fortaleza, Ceara, Brazil. Presented at: 6th World Congress of the World Society for Pediatric Infectious Diseases, November 21, 2009; Buenos Aires, Argentina.

Author: Lima I, Soares AM, Silva-Filho JQ, Weigl BH, Rey LC, Lima A

Publication date: November 2009

Region: Global

This fact sheet summarizes the Infant & Young Child Nutrition Project's approach to designing and implementing infant feeding and HIV activities.

Publication date: November 2009

Region: Global

A visual display charting some diagnostic technologies (e.g., PCR, ELISA, Lumora, TwistDx, and nonintstrumented nucleic acid amplification (NINA) on axes of performance and reach (the ability to function in low-resource areas).  Presented at PATH, January 10, 2010; Seattle, WA.

Author: Weigl B

Publication date: November 2009

Region: Global

This fact sheet provides information about the use of the hormone oxytocin in the Uniject device to prevent postpartum hemorrhage. It summarizes the benefits of using this innovative solution and also provides a success story based on a pilot study conducted in Mali.

Publication date: November 2009

Region: Global

Improving iron status among infants and young children is of continued concern in low- to middle-income countries. This article, published in The Journal of Nutrition, reports on a double-blind, randomized trial among mildly anemic children in Brazil that compared use of rice fortified with micronized ferric pyrophosphate using the Ultra Rice technology with identical nonfortified rice. The study found that, in populations where young children are routinely fed approximately 100 grams of cooked rice daily, fortifying rice with iron may improve iron status at least as well as providing free iron drops.

Author: Beinner M, Velasquez-Meléndez G, Pessoa MC, Greiner T

Publication date: November 2009

Region: Global

This document describes PATH's approach to maximizing the availability, accessibility, and affordability of global health technologies through private-sector collaboration. This approach is critical in enabling global access of the results of our private-sector partnerships. This edition is a condensed version of the 12-page document, Bringing New Health Technologies Within Reach for Everyone. It is supported by six case studies illustrating how PATH has applied this approach to a food-fortification technology, pneumococcal vaccines, human papillomavirus screening, Japanese encephalitis vaccines, malaria vaccines, and the Uniject® prefilled injection device.

Publication date: November 2009

Region: Global

As more developing countries take on responsibility for purchasing health commodities, requisite capabilities—such as decision-making, planning, and technical skills—often require strengthening. To address this need, PATH developed the comprehensive Procurement Capacity Toolkit for those responsible for and involved in the supply of reproductive health products. The toolkit is available as one large file or, for faster downloading, 17 smaller files.

Publication date: November 2009

Region: Global

The Optimize project, a collaboration between PATH and the World Health Organization, commissioned this white paper to examine the issues influencing vaccine producer willingness to advance, adopt, and commercialize value-added technologies for vaccines for low-income and lower-middle-income country markets.

Author: Gilchrist S

Publication date: November 2009

Region: Global

The Prevention of Postpartum Hemorrhage Initiative (POPPHI), funded by USAID, developed this document to summarize the projects and activities that took place over its five-year history. The report focuses on the challenge of postpartum hemorrhage and the mechanisms developed by POPPHI to address it. It also provides an overview of the tools, including resources and policy changes, that were accomplished. Finally, the document also highlights specific work done by PATH, its partners, and the POPPHI team in scale-up and small grant countries. The report is available as one large file or as four smaller files for easier downloading.

Publication date: November 2009

Region: Global

Clinical trials are a critical source of data for decisions around vaccine development. This fact sheet provides information about the phases of clinical trials.

Publication date: October 2009

Region: Global

Under the Making Medical Injections Safer project, PATH has supported ministries of health and environment to develop the systems needed for effective health care waste management. This paper describes the process, tools, and strategies used to successfully engage PEPFAR partners in Uganda and Nigeria to improve health care waste management.

Publication date: October 2009

Region: Africa

This fact sheet provides an overview of PATH's work to enhance the capacity of pharmacies to strengthen community health throughout Vietnam. Through trainings and supportive supervision, PATH is working to strengthen a vital source of health information and services in Vietnam.

Publication date: October 2009

Region: Asia

This document provides a brief overview of the Optimize project’s strategy for developing delivery systems that are as advanced and innovative as the vaccines they support. Project Optimize, a collaboration between the World Health Organization and PATH, has been given a unique mandate to think far into the future: to put technological and scientific advances to work, helping define the ideal characteristics and specifications for health products; and to create a vaccine supply chain that is flexible and robust enough to handle an increasingly large and costly portfolio of vaccines.

Publication date: October 2009

Region: Global

This poster and accompanying handout, presented by the IYCN Project at the 10th Commonwealth Association of Paediatric Gastroenterology and Nutrition Congress on Diarrhoea & Malnutrition in August 2009, make a case for investing in prevention of severe acute malnutrition (SAM) rather than in the universal introduction of SAM treatment.

Publication date: September 2009

Region: Global

This briefing paper underscores the burden of rotavirus and highlights the promise of vaccines to combat the virus as the global health community prepares for worldwide introduction.  

Publication date: September 2009

Region: Global

This guide introduces a new approach to developing communication strategies at PATH. The SIM process—derived from strategy development, intervention redesign, and monitoring and evaluation—represents a first attempt to systematize three concurrent and interlinked strands of activity in the start-up phase of PATH communication-for-social-change projects. The SIM process is the result of learning from more than a decade of communication programming in the Kenya Country Program, refined and augmented through consultations with communications professionals in other PATH projects worldwide.

Author: Bingham A, Brawley M, Gopinath CY

Publication date: September 2009

Region: Global