Part of the Technology Updates series, this fact sheet describes PATH's work on cryotherapy for cervical cancer prevention.

Publication date: April 2012

Region: Global

Part of series: Technology Updates

DefeatDD.org is an interactive website aimed at informing and inspiring advocates committed to joining their voices and raising awareness about diarrheal disease. The website hosts a weekly blog about advances in diarrheal disease control and provides key documents and links to information on simple, lifesaving interventions that have the potential to significantly impact diarrhea incidence worldwide.

Publication date: 2013

Region: Global

Part of series: Websites

From tracking tuberculosis in Africa to providing better maternal and child health care in India, PATH's work in health information systems is bridging the gap between global health and information and communication technology using a different approach—a user-driven enterprise architecture and technology that addresses user requirements.

Publication date: June 2011

Region: Global

Project Optimize, a collaboration between PATH and the World Health Organization, undertook a cost-comparison case study of five container options for vaccine transport from the national to the regional level in Senegal. This report may be used as a starting point for other country vaccine programs weighing transport options in the face of increasing vaccine volume.

Author: Lorenson K, Mvundura M

Publication date: January 2013

Region: Global

Part of the Technology Updates series, this fact sheet describes delivery kit work at PATH.

Publication date: January 2008

Region: Global

Part of series: Technology Updates

PATH and Vietnam's National Expanded Program on Immunization pilot tested the use of a needle-remover device in rural Vietnam. This fact sheet reports on health workers' experience that needle removers were easy to operate, safe, and effective for treating contaminated syringes at health centers and in the community.

Publication date: 2007

Region: Asia

Author: Lloyd J; Wittet S; Lasher H

Publication date: 2003

Region: Global

This poster presents a study to collect and characterize specimens from febrile patients who were suspected to have malaria, pedigree specimens against a panel of nucleic acid and serological markers, and draw early insights into data that would be generated by a multiplex diagnostic platform. Presented at The American Society of Tropical Medicine and Hygiene, December 7, 2008; New Orleans, LA.

Author: Gerlach JL, Waitumbi J, Koros J, et al

Publication date: December 2008

Region: Global

This poster demonstrates the predictive validity of an assay developed by Arbor Vita and PATH. For this study, cervical swab specimens collected from women screened, diagnosed, and managed in rural settings in China were tested for the presence of HPV-16 DNA then examined for HPV16-E6 expression. Results confirmed E6 is a potential diagnostic marker. Presented at: 23rd Papillomavirus Conference and Clinical Workshop, September 1, 2006; Prague, Czech Republic.

Author: Schweizer J, Somoza C, Mahoney C, et al

Publication date: September 2006

Region: Global

Recombinase Polymerase Amplification (RPA) assays were designed to detect pol from HIV-1BRU proviral DNA using real-time or immunochromatographic strip detection of RPA amplicons. Presented at: AACC 41st Annual Oak Ridge Conference, April 16, 2009; Baltimore, MD.

Author: Boyle DS, Lehman DA, Overbaugh J, et al

Publication date: April 2009

Region: Global

This poster outlines the evaluation of two immunochromatographic strip test platforms for the best limit of detection: one uses an antibody colloidal gold conjugate which is visually interpreted yielding qualitative results, and the other uses an antibody paramagnetic particle conjugate which is read by an instrument yielding quantitative results. The resulting limits of detection of these two methods are compared to the target limit of detection for an E6 assay of ~50 pg. Presented at: 23rd Papillomavirus Conference and Clinical Workshop, September 1, 2006; Prague, Czech Republic.

Author: Peck R, Weigl BH, Schweizer J, et al

Publication date: September 2006

Region: Global

A report on the selection and evaluation of target markers for a multiplex diagnostic platform under development. Based on the DxBox platform being developed as part of a public-private consortium lead by the University of Washington. Presented at the Molecular Medicine Tri-Conference, March 25, 2008; San Francisco, CA.

Author: Gerlach JL, Anyona S, Koros J, et al

Publication date: March 2008

Region: Global

A report on appropriate product specifications and the challenges of introducing a point-of-care multiplexed diagnostic platform in low-resource settings in developing countries. Based on the DxBox platform being developed as part of a public-private consortium lead by the University of Washington. Presented at: Molecular Medicine Tri-Conference, March 25, 2008; San Francisco, CA.

Author: de los Santos T, Crudder C, Metzler M, Gerlach J, Steele M, Domingo GJ

Publication date: March 2008

Region: Global

Facilitated by project Optimize and conducted by a multidisciplinary group of partners, these landscape analyses highlight ongoing work related to five priority areas that comprise the vision for immunization supply systems in 2020. The analyses also highlight critical gaps that need to be addressed to achieve the vision. The five priority areas are vaccine and related products, supply system design, environmental impact, information systems, and human resources. The document is available as one large file or as six smaller files for easier downloading.

Publication date: June 2011

Region: Global

Part of the Technology Updates series, this fact sheet describes PATH's work on developing an affordable sanitary pad made out of common agricultural waste materials.

Publication date: April 2012

Region: Global

Part of series: Technology Updates

This document briefly describes the core components needed to introduce and use needle removers in a safe and sustainable manner.

Author: Berman A

Publication date: 2007

Region: Asia

PATH is working to provide safe water at the community level. The Smart Electrochlorinator 200 (SE200) is a device that allows communities to take ownership of the safety of their drinking water while potentially creating income opportunities for local entrepreneurs. This project brief summarizes PATH's work facilitating the development and implementation of the SE200.

Author: Kols A

Publication date: July 2011

Region: Global

Part of series: Safe water briefs

A prototype of a novel diagnostic assay for cervical pre-cancer and cancer has been developed in both a sandwich ELISA-based and a lateral flow–based format (“strip test”). The test specifically detects presence of high-risk HPV-E6 and therefore promises to be of higher predictive value for cervical pre-cancer and cancer than other assays detecting merely presence of HPV. Presented at: 22rd International Papillomavirus Conference and Clinical Workshop, September 1, 2006; Vancouver, Canada.

Author: Schweizer J, Somoza C, Peck R, et al

Publication date: September 2006

Region: Global

This article was published in Vaccine, Volume 27, Issue 1, Jones Braun L, Tyagi A, Perkins S, et al, Development of a freeze-stable formulation for vaccines containing aluminum salt adjuvants, pp. 72-79, Copyright Elsevier (2009). The journal may be accessed at http://www.sciencedirect.com/science/journal/0264410X. 

Author: Jones Braun L, Tyagi A, Perkins S, et al

Publication date: January 2009

Region: Global

This poster reports progress incorporating magnetic beads within a unique lab card that permits efficient capture and enrichment of E. coli O157:H7 from feces. Presented at the 106th General Meeting of the American Society for Microbiology, May 21, 2006; Orlando, FL.

Author: Gerdes JC, Weigl BH, Yager P

Publication date: May 2006

Region: Global