The Cold Chain Equipment Manager (CCEM) is a Microsoft Access–based software tool. It is accompanied by a user manual, data collection questionnaires, a surveyor’s guide to these questionnaires, and an equipment identification guide. CCEM also comes with practice files, providing new users with practice data to demonstrate how CCEM will analyze cold chain equipment data and facilitate multiyear equipment planning. CCEM version 2.1 is available for download (see below) or, to request a copy on CD, email CCEMinfo@path.org. For more information, please see the CCEM project description.

Publication date: January 2012

Region: Global

Human papillomavirus (HPV) vaccine is intended to prevent cervical cancer. As part of project Optimize, a two-year HPV vaccine demonstration project is being conducted to demonstrate how existing delivery systems can be adapted to successfully provide HPV vaccine to young adolescent girls. HPV vaccine is a strong candidate for out-of-the-cold-chain use given its characteristics of high heat stability and freeze sensitivity.

Author: Robertson J, Vu H, Le N, et al.

Publication date: July 2010

Region: Global

Project Optimize—a collaboration between the World Health Organization and PATH—aims to employ technological and scientific advances in the immunization field. This document describes efforts to define ideal specifications for health products and create a flexible and robust vaccine supply chain that can handle an increasingly large and costly portfolio of vaccines.

Publication date: November 2010

Region: Global

This fact sheet provides an overview of PATH's ongoing work in Cambodia to integrate diarrhea and pneumonia control. At the national level, PATH collaborated with the Cambodia Ministry of Health to strengthen policy so that effective interventions and appropriate and reliable supplies are made available throughout the public- and private-health sectors as well as in the community to reduce the burden of diarrheal disease and pneumonia among children in Cambodia. PATH also worked on a district-level demonstration project to put policy into practice and inform expansion throughout the country. Through this integrated approach to community health, Cambodia is addressing the two most dangerous threats to its children and is already making a significant and lasting impact.

Publication date: March 2012

Region: Asia

This briefing paper underscores the burden of rotavirus and highlights the promise of vaccines to combat the virus as the global health community prepares for worldwide introduction.  

Publication date: September 2009

Region: Global

Malaria is a leading cause of morbidity and mortality in children younger than five years in Kenya. Within the context of planning for a vaccine to be used alongside existing malaria control methods, this study, published in Malaria Journal, explores sociocultural and health communications issues among individuals who are responsible for or influence decisions on childhood vaccination at the community level.

Author: Ojakaa DI, Ofware P, Machira YW, et al

Publication date: May 2011

Region: Africa

This fact sheet highlights PATH's work to address rotavirus, the leading cause of severe diarrheal disease. It includes general information about our efforts to increase access to and effectiveness of existing vaccines, as well as to develop new vaccines.

Publication date: July 2011

Region: Global

Part of series: Diarrheal disease fact sheets

This report is part of the Cervical Cancer Prevention: Practical Experience Series summarizing lessons learned to guide cervical cancer prevention program planning in low-resource settings. It demonstrates that formative research is a necessary component of overall planning, discusses formative research issues specific to cervical cancer, and explains how research results may be used for strategic planning within the cervical cancer context.

Publication date: 2012

Region: Global

This fact sheet summarizes PATH's projects in Vietnam that aimed to reduce childhood illness and death from diarrhea. Efforts included collaborations to update guidelines for health workers, clinical trials of rotavirus vaccines, and household water treatment and storage activities.

Publication date: May 2012

Region: Asia

Part of series: Diarrheal disease fact sheets

Keeping heat-sensitive vaccines and other drugs at the right temperature is crucial yet often difficult in areas with limited or no electrical power. In response to this challenge, a group of public- and private-sector partners is working with project Optimize to evaluate a range of transportation and storage containers for heat-sensitive drugs and vaccines that operate in environments with or without access to reliable power.

Publication date: July 2012

Region: Global

This fact sheet makes the case for why vaccines are a critical, cost-effective investment for improving global health and saving children's lives.

Publication date: July 2012

Region: Global

This paper describes research into the anticipated processes and data needed to inform decision-making on malaria vaccines, the most advanced of which is still in phase 3 trials.

Author: Brooks A, Ba-Nguz A

Publication date: February 2012

Region: Africa

This document provides details on PATH's partnership with the National Expanded Program on Immunization in Vietnam to enhance surveillance of Japanese encephalitis disease and inform planning for immunization programs.

Author: Phillips D

Publication date: May 2007

Region: Asia

This 72-page document offers an in-depth look at vaccines against human papillomavirus (HPV), both currently available vaccines and those in development, including therapeutic vaccines. The document includes an examination of programmatic issues relevant to developing countries.

Author: Kols A

Publication date: 2006

Region: Global

DefeatDD’s weekly blog features posts from PATH staff and partners about the burden of diarrheal disease and the solutions to defeat it, including trends in child health, success stories, news, and personal perspectives.

Publication date: 2013

Region: Global

Part of series: Blogs

DefeatDD.org is an interactive website aimed at informing and inspiring advocates committed to joining their voices and raising awareness about diarrheal disease. The website hosts a weekly blog about advances in diarrheal disease control and provides key documents and links to information on simple, lifesaving interventions that have the potential to significantly impact diarrhea incidence worldwide.

Publication date: 2013

Region: Global

Part of series: Websites

Project Optimize, a collaboration between PATH and the World Health Organization, undertook a cost-comparison case study of five container options for vaccine transport from the national to the regional level in Senegal. This report may be used as a starting point for other country vaccine programs weighing transport options in the face of increasing vaccine volume.

Author: Lorenson K, Mvundura M

Publication date: January 2013

Region: Global

Facilitated by project Optimize and conducted by a multidisciplinary group of partners, these landscape analyses highlight ongoing work related to five priority areas that comprise the vision for immunization supply systems in 2020. The analyses also highlight critical gaps that need to be addressed to achieve the vision. The five priority areas are vaccine and related products, supply system design, environmental impact, information systems, and human resources. The document is available as one large file or as six smaller files for easier downloading.

Publication date: June 2011

Region: Global

This fact sheet highlights PATH's work to develop safe, effective, and affordable vaccines against Shigella and enterotoxigenic Escherichia coli, two of the leading bacterial causes of diarrheal disease.

Publication date: June 2011

Region: Global

Part of series: Diarrheal disease fact sheets

This fact sheet outlines PATH's pneumococcal vaccine project from a technical perspective. It includes an overview of PATH's vaccine development portfolio, research activities, and partners to support the development of vaccines against pneumococcal disease that can be effective and affordable for children in the developing world.

Publication date: February 2012

Region: Global