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Total results with these characteristics: 86

Subject: Vaccines and immunization > Diarrheal disease

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Outsourcing the Vaccine Supply Chain and Logistics System to the Private Sector: The Western Cape Experience in South Africa

Facilitated by project Optimize, a World Health Organization and PATH collaboration, this review was conducted in the Western Cape of South Africa whereby the Biovac Institute (a third-party, private-sector company) took over the roles of vaccine procurement, warehouse management, inventory management, and vaccine distribution directly to health centers.

Author: Lydon P

Publication date: October 2011

Region: Africa

PATH Today (Fall 2011)

This edition of PATH Today features our work to protect children from diarrheal disease, the use of mobile devices to diagnose tuberculosis and improve maternal health, and a profile of PATH donor Ann Hayes. The issue also provides information about our yearly reports to donors, workplace and planned giving, and the results of the meningitis vaccine campaign launch in sub-Saharan Africa.

Publication date: September 2011

Region: Global

Part of series: PATH Today

Diarrheal Disease and Childhood Pneumonia in Cambodia

Childhood pneumonia and diarrheal disease are the two leading causes of preventable deaths among children under the age of five in Cambodia and around the world. This fact sheet gives an overview of how PATH is working on an integrated approach to the prevention and treatment of these two illnesses in Cambodia.

Publication date: August 2011

Region: Asia

An Integrated Approach to Confronting Diarrheal Disease

This briefing paper provides an overview of the tools and interventions involved with an integrated approach to diarrheal disease control, including vaccines, oral rehydration, breastfeeding, and zinc treatment. The document also advocates for renewed commitment at global, regional, and national levels.

Publication date: July 2011

Region: Global

Part of series: Diarrheal disease fact sheets

Directions in Global Health (Volume 8, Issue 1)

This issue of Directions in Global Health features PATH’s work related to vaccines and immunization. Articles cover the development and introduction of a vaccine to eliminate epidemic meningitis in Africa, use of vaccines and other interventions to prevent cervical cancer, transformation of vaccine distribution systems, expansion of access to rotavirus vaccines, and advancements in vaccine technologies.

Publication date: May 2011

Region: Global

Part of series: Directions in Global Health

Vesikari Clinical Severity Scoring System Manual

This manual provides a suggested standardized methodology for implementing the Vesikari Clinical Severity Scoring System across rotavirus vaccine studies. It provides details on scoring system parameters, identifies implementation challenges, and presents instructions for collecting symptom information and using the accompanying template Case Report Form and diary cards.

Author: Lewis K

Publication date: May 2011

Region: Global

The Case for Investment in Enterotoxigenic Escherichia coli Vaccines

This market assessment aims to increase the awareness of biotechnology and pharmaceutical companies worldwide about the opportunities and potential markets that exist for low-cost and effective vaccines against enterotoxigenic Escherichia coli (ETEC). In addition, it provides donors and commercial investors with a better understanding of the potential risks, rewards, and gaps in knowledge relative to these opportunities as they consider their own investment strategies. The resulting analysis demonstrates that ETEC vaccines may represent a moderate opportunity for industry investment with an estimated annual revenue potential of more than US$600 million ten years after global launch.

Publication date: March 2011

Region: Global

Improving Health for Families Everywhere: PATH Reaches Mothers, Children, and Communities With Key Innovations for Strong Futures

PATH has worked to improve maternal and child health, nutrition, and family planning in developing countries for more than 30 years. This brochure describes our integrated approach to reach mothers, children, and communities with key innovations for strong futures.

Publication date: May 2010

Region: Global

Common Virus and Senseless Killer: A Briefing Paper on Rotavirus

This briefing paper underscores the burden of rotavirus and highlights the promise of vaccines to combat the virus as the global health community prepares for worldwide introduction.  

Publication date: September 2009

Region: Global

PATH Today (Fall 2009)

This edition of PATH Today highlights work to improve children’s health in Nicaragua and Kenya and spotlights PATH's safe water project in Korogocho, a slum near Nairobi, Kenya. It also includes brief updates on the 2009 Breakfast for Global Health, workplace giving, an influenza vaccine study in Africa, and PATH's 2008 annual report.

Publication date: September 2009

Region: Global

Part of series: PATH Today

Diarrheal Disease: Solutions to Defeat a Global Killer

Diarrheal Disease: Solutions to Defeat a Global Killer presents scientific evidence to support strategies to scale up use of interventions, including safe water, improved sanitation and hygiene, breastfeeding and optimal complementary feeding, rotavirus vaccines, zinc treatment, and oral rehydration therapy/oral rehydration solution. In addition, the report features case studies of on-the-ground programs that bring these tools to communities that need them most. The document is available as one large file or as three smaller files for easier downloading.

Publication date: May 2009

Region: Global

Directions in Global Health (Volume 5, Issue 3)

This issue of Directions in Global Health describes PATH's work to control and prevent diarrheal disease, reach out to young scouts in Kenya and Uganda with HIV/AIDS information, assess the impact of malaria control efforts in Zambia, conduct DHS surveys, and shape HPV vaccine introduction in Peru.

Author: PATH

Publication date: December 2008

Region: Global

Part of series: Directions in Global Health

Efficacy of Standard Methods for Water Testing at a Range of Nonstandard Temperature

Fifteen strains of Escherichia coli from various geographical areas, animal, and soil sources were tested on standard and nonstandard detection assays at temperatures from 23°C to 45°C to test the viability of currently available E. coli tests in low-resource settings. Presented at the American Society for Microbiology Conference, June 1, 2008; Boston, MA.

Author: Allen E, Dillman L, Weigl B

Publication date: June 2008

Region: Global

Rotavirus Vaccines

This fact sheet aims to raise awareness about two new vaccines against rotavirus, a major cause of diarrheal disease. One in a set of introductory resources, it provides stakeholders and policymakers in the world’s poorest countries with crucial information on new tools to fight diarrheal disease.

Publication date: January 2008

Region: Global

Part of series: Diarrheal disease fact sheets

Introduction of Rotavirus Vaccine with Support from the GAVI Alliance: Information to Assist the National Decision-Making and Application Process

This guide summarizes considerations for rotavirus vaccine introduction in Eastern European countries eligible for support from the GAVI Alliance.

Publication date: December 2007

Region: Eastern Europe

Directions in Global Health (Volume 4, Issue 1)

This special issue of Directions in Global Health highlights PATH's vaccine partnership efforts: PATH Malaria Vaccine Initiative (MVI), pneumococcal vaccine development project, Meningitis Vaccine Project, cervical cancer vaccine project, and Rotavirus Vaccine Program. The issue also features a case study of the vaccine vial monitor.

Author: PATH

Publication date: May 2007

Region: Global

Part of series: Directions in Global Health

The PATH Rotavirus Vaccine Program: Equal Protection Against a Childhood Threat

This fact sheet provides an update on the activities of the PATH Rotavirus Vaccine Program, which aims to dramatically reduce the typical 10- to 15-year timeline between introduction of new vaccines in wealthy countries and their availability in the developing world. Activities include measuring disease burden, determining vaccine efficacy and safety in developing countries, communicating the value of rotavirus vaccines, and generating information on the health economics of rotavirus vaccination.

Author: Phillips D

Publication date: April 2007

Region: Global

Lab-on-a-Card Assay for Enteric Pathogens

We describe the functional elements of a diagnostic instrument and disposable enteric card system under development that rapidly identifies and differentiates Shigella, E. coli, Campylobacter, and Salmonella in stool samples. These elements, currently realized as microfluidic subcircuits on individual cards, are: (1) pathogen capture and lysing, (2) nucleic acid capture, (3) on-chip rapid PCR, and (4) lateral flow detection of amplicons. Presented at the Solid State Sensor, Actuator and Microsystems Workshop, June 4, 2006; Hilton Head Island, SC.

Author: Weigl BH, Gerdes JC, Tarr P, et al

Publication date: June 2006

Region: Global

Device for Automated Capture of E. coli O157:H7 From Feces: Feasibility for Point-of-Care Detection

This poster reports progress incorporating magnetic beads within a unique lab card that permits efficient capture and enrichment of E. coli O157:H7 from feces. Presented at the 106th General Meeting of the American Society for Microbiology, May 21, 2006; Orlando, FL.

Author: Gerdes JC, Weigl BH, Yager P

Publication date: May 2006

Region: Global

PATH Today (Spring 2006)

This edition of PATH Today features the articles "A laboratory on a card," "Using microfluidic tests to identify infection," and "Common proteins for common prevention," which highlights the work of John Boslego and his team on pneumococcus. It also includes a letter from donor Shannon Scopa about her family's ordeal with rotavirus.

Publication date: May 2006

Region: Global

Part of series: PATH Today

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