The study highlighted in this project Optimize report uses a breakeven cost analysis to compare potential prices, wastage rates, and cold chain requirements for various human papillomavirus (HPV) vaccine presentations.

Publication date: August 2010

Region: Global

Supported by a seed grant from the World Bank, PATH began to focus on cervical cancer in 1991. Since then, our portfolio has expanded tremendously, thanks in large part to grants from the Bill & Melinda Gates Foundation. In this report, we describe our key cervical cancer prevention initiatives.

Publication date: April 2013

Region: Global

PATH’s key areas of work in cervical cancer prevention are described in depth in this 12-page publication.

Publication date: August 2008

Region: Global

This fact sheet provides an overview of PATH's work to prevent and treat cervical cancer in Vietnam, including human papillomavirus vaccine introduction research, vaccine demonstration, a screening and treatment pilot model, and advocacy.

Publication date: May 2011

Region: Asia

The Cold Chain Equipment Manager (CCEM) is a Microsoft Access–based software tool. It is accompanied by a user manual, data collection questionnaires, a surveyor’s guide to these questionnaires, and an equipment identification guide. CCEM also comes with practice files, providing new users with practice data to demonstrate how CCEM will analyze cold chain equipment data and facilitate multiyear equipment planning. CCEM version 2.1 is available for download (see below) or, to request a copy on CD, email CCEMinfo@path.org.

Publication date: January 2012

Region: Global

Human papillomavirus (HPV) vaccine is intended to prevent cervical cancer. As part of project Optimize, a two-year HPV vaccine demonstration project is being conducted to demonstrate how existing delivery systems can be adapted to successfully provide HPV vaccine to young adolescent girls. HPV vaccine is a strong candidate for out-of-the-cold-chain use given its characteristics of high heat stability and freeze sensitivity.

Author: Robertson J, Vu H, Le N, et al.

Publication date: July 2010

Region: Global

This report is part of the Cervical Cancer Prevention: Practical Experience Series on the RHO Cervical Cancer website summarizing lessons learned to guide cervical cancer prevention program planning in low-resource settings. It demonstrates that formative research is a necessary component of overall planning, discusses formative research issues specific to cervical cancer, and explains how research results may be used for strategic planning within the cervical cancer context.

Publication date: 2012

Region: Global

This 72-page document offers an in-depth look at vaccines against human papillomavirus (HPV), both currently available vaccines and those in development, including therapeutic vaccines. The document includes an examination of programmatic issues relevant to developing countries.

Author: Kols A

Publication date: 2006

Region: Global

The journal Vaccine published a special supplement on the Decade of Vaccines Global Vaccine Action Plan (GVAP) that features articles by PATH contributors and others on the GVAP strategic objectives and the opportunities and challenges associated with its implementation. The 27 articles cover a range of related topics, including vaccine development, financing, access, delivery, and health impact. More than 100 authors contributed to the supplement representing a variety of international and developing-country stakeholders, from civil society and academia to vaccine manufacturers and policymakers.

Author: Glassman A, Zoloa JI, Duran D, et al

Publication date: April 2013

Region: Global

This special issue of Directions in Global Health highlights PATH's vaccine partnership efforts: PATH Malaria Vaccine Initiative (MVI), pneumococcal vaccine development project, Meningitis Vaccine Project, cervical cancer vaccine project, and Rotavirus Vaccine Program. The issue also features a case study of the vaccine vial monitor.

Author: PATH

Publication date: May 2007

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health features PATH’s work related to vaccines and immunization. Articles cover the development and introduction of a vaccine to eliminate epidemic meningitis in Africa, use of vaccines and other interventions to prevent cervical cancer, transformation of vaccine distribution systems, expansion of access to rotavirus vaccines, and advancements in vaccine technologies.

Publication date: May 2011

Region: Global

Part of series: Directions in Global Health

This unit of the Cervical Cancer Prevention: Practical Experience Series on the RHO Cervical Cancer website provides methods and tools for designing and conducting an evaluation of a human papillomavirus (HPV) vaccination pilot or demonstration project. It also gives practical examples of using the results to refine an HPV vaccine delivery strategy for national scale-up.

Publication date: 2012

Region: Global

This report is a synthesis of the project Evaluating HPV Vaccine Delivery Strategies in Vietnam, which aimed to identify appropriate strategies for human papillomavirus (HPV) vaccine delivery in different geographic and socioeconomic conditions. The report summarizes results of both the implementation and research aspects of the project. The document is available as one large file or as four smaller files for easier downloading.

Publication date: December 2010

Region: Asia

The Global Vaccine Action Plan (GVAP)—endorsed by the 194 Member States of the World Health Assembly in May 2012—is a roadmap to prevent millions of deaths by 2020 through more equitable access to vaccines for people in all communities. The GVAP aims to strengthen routine immunization, introduce new and improved vaccines, and advance research and development for the next generation of vaccines and technologies.

Author: Decade of Vaccines Collaboration

Publication date: May 2012

Region: Global

This report summarizes the human papillomavirus (HPV) vaccination program implemented in Uganda by PATH, the Uganda National Expanded Program on Immunization of the Ministry of Health, and the Child Health and Development Centre, through the HPV Vaccines: Evidence for Impact project. HPV vaccine was made available to almost 10,000 girls in select parts of the country. The purpose of the study was to investigate operational issues related to HPV vaccination of young adolescent girls, aimed at identifying effective and cost-effective strategies. This report interprets the results and summarizes helpful lessons for policymakers and program managers, especially those in sub-Saharan Africa, looking to shape their own HPV vaccination programs. To see other reports in this series, visit the RHO Cervical Cancer website.

Publication date: January 2011

Region: Global

Part of series: HPV vaccination project lessons learned reports

This report summarizes the human papillomavirus (HPV) vaccination program implemented in Peru by PATH, Instituto de Investigación Nutricional, and Ministerio de Salud de Peru, Estrategia Sanitaria Nacional de Inmunizaciones through the HPV Vaccines: Evidence for Impact project. HPV vaccine was made available to all girls aged nine years or older in grade 5 in selected parts of the country. The purpose of the study was to investigate operational issues related to HPV vaccination of young adolescent girls, aimed at identifying effective and cost-effective strategies. The publication will be useful for policymakers and program managers around the world, and especially in Latin America, who are designing public-sector HPV vaccination programs. To see other reports in this series, visit the RHO Cervical Cancer website.

Publication date: December 2010

Region: Global

Part of series: HPV vaccination project lessons learned reports

This report summarizes the human papillomavirus (HPV) vaccination program implemented in Vietnam by PATH, the Vietnam National Institute of Hygiene and Epidemiology, and the Vietnam National Center for Health Education and Communication through the HPV Vaccines: Evidence for Impact project. The purpose of the study was to investigate operational issues related to HPV vaccination of young adolescent girls, aimed at identifying effective and cost-effective strategies. This report interprets the results and summarizes helpful lessons for policymakers and program managers, especially those in Southeast Asia, looking to shape their own HPV vaccination programs. To see other reports in this series, visit the RHO Cervical Cancer website.

Publication date: November 2012

Region: Asia

Part of series: HPV vaccination project lessons learned reports

Financing the human papillomavirus (HPV) vaccine and mobilizing resources to support new delivery mechanisms will constitute some of the most significant challenges to achieving widespread HPV vaccination in the developing world. Country decision-makers will need to weigh the value of HPV vaccines against other national health priorities, against other vaccines entering the market, and, for some countries, against expanding coverage of existing vaccines. With these cost and financing obstacles resolved, developing countries would be able to build robust programs to immunize adolescents and thus dramatically reduce the incidence of cervical cancer.

Publication date: December 2007

Region: Global

This document offers practical information to countries that plan to pilot, expand, or scale up human papillomavirus (HPV) vaccination programs. The main focus is on issues specific to HPV vaccination, such as working with a young adolescent target population in school settings and developing community support for HPV vaccination programs.

Publication date: 2011

Region: Global

This fact sheet outlines PATH's work on vaccines and immunization. Topic areas include developing affordable vaccines, designing innovative vaccine technologies, and expanding uptake of existing vaccines. These efforts reduce the burden of malaria, meningitis, diarrheal disease, Japanese encephalitis, pneumococcal disease, influenza, rotavirus, polio, respiratory syncytial virus (RSV), and other infectious diseases in developing countries.

Publication date: December 2013

Region: Global

Part of series: PATH's areas of focus fact sheets