The Optimize project, a collaboration between PATH and the World Health Organization, commissioned this white paper to examine the issues influencing vaccine producer willingness to advance, adopt, and commercialize value-added technologies for vaccines for low-income and lower-middle-income country markets.

Author: Gilchrist S

Publication date: November 2009

Region: Global

This four-page brochure tells the story of the Uniject device--how it grew from a concept to an easy-to-use, all-in-one injection device that will be used to vaccinate every newborn in Indonesia against hepatitis B and to help eliminate maternal and neonatal tetanus globally. The publication covers the development, evaluation, licensing, production, and design and function of Uniject. Photographs and a timeline of Uniject's history included.

Author: E.Simpson

Publication date: 2003

Region: Global

Part of the Technology Updates series, this fact sheet describes PATH's work on single-dose, prefilled reconstitution devices (SPRDs). SPRDs can make reconstitution of critical vaccines safer and more economical and can help eliminate adverse events or wastage that can occur with improper reconstitution, which also reduces impact on the medical waste disposal system.

Publication date: May 2012

Region: Global

Part of series: Technology Updates

Project Optimize, a collaboration between the World Health Organization and PATH, aims to provide national immunization programs with recommendations to build integrated health supply systems, including strategic linkages with the parastatal and private sector. Ultimately, integration will allow public health programs to reduce uncertainties and risks, achieve economies of scale, shorten delivery lead times, improve procurement, provide better incentives for health workers, and improve quality of service to clients.

Publication date: July 2012

Region: Global

The fourth annual policy report from the Global Health Technologies Coalition outlines actions the United States can take to help reduce deaths, extend lives, and secure healthier futures by supporting research for new health tools.

Publication date: February 2013

Region: North America and Europe

Part of series: GHTC's annual policy reports

The purpose of this project Optimize survey was to obtain input from stakeholders within the Expanded Programme on Immunization in Vietnam about issues and perceptions related to the storage, distribution, and delivery of the current and potential options for human papillomavirus vaccine presentation and packaging.

Publication date: December 2009

Region: Asia

In this document, project Optimize reviews the US Centers for Disease Control and Prevention’s (CDC’s) Vaccine Management Business Improvement Project, which represents an end-to-end reengineering of the US public-sector vaccine supply chain—from vaccine budgeting through storage and distribution. The CDC’s overarching goal was to ensure that vaccine was flowing to the right places at the right time.

Author: Wasserman N

Publication date: November 2010

Region: Global

This fact sheet provides an overview of rotavirus disease and vaccines in Africa. It includes information about the tremendous burden of rotavirus diarrhea in African children, rotavirus diarrhea treatment and prevention strategies, and the effectiveness of rotavirus vaccines. It also lists countries that have introduced rotavirus vaccines into their national immunization programs.

Publication date: October 2012

Region: Africa

Part of series: Rotavirus disease and vaccines fact sheets

This fact sheet provides an overview of rotavirus disease and vaccines in Asia. It includes information about the tremendous burden of rotavirus diarrhea in Asian children, rotavirus diarrhea treatment and prevention strategies, and the effectiveness of rotavirus vaccines. It also lists countries that have introduced rotavirus vaccines into their national immunization programs.

Publication date: October 2012

Region: Asia

Part of series: Rotavirus disease and vaccines fact sheets

This fact sheet provides an overview of rotavirus disease and vaccines in Ghana. It includes information about the tremendous burden of rotavirus diarrhea in Ghanaian children, rotavirus diarrhea treatment and prevention strategies, and the effectiveness of rotavirus vaccines. It also lists countries that have introduced rotavirus vaccines into their national immunization programs.

Publication date: January 2013

Region: Africa

Part of series: Rotavirus disease and vaccines fact sheets

This fact sheet provides an overview of rotavirus disease and vaccines in Haiti. It includes information about the tremendous burden of rotavirus diarrhea in Haitian children, rotavirus diarrhea treatment and prevention strategies, and the effectiveness of rotavirus vaccines. It also lists countries that have introduced rotavirus vaccines into their national immunization programs.

Publication date: April 2013

Region: Latin America

Part of series: Rotavirus disease and vaccines fact sheets

This fact sheet provides an overview of rotavirus disease and vaccines in Malawi. It includes information about the tremendous burden of rotavirus diarrhea in Malawian children, rotavirus diarrhea treatment and prevention strategies, and the effectiveness of rotavirus vaccines. It also lists countries that have introduced rotavirus vaccines into their national immunization programs.

Publication date: October 2012

Region: Africa

Part of series: Rotavirus disease and vaccines fact sheets

This fact sheet provides an overview of rotavirus disease and vaccines in Tanzania. It includes information about the tremendous burden of rotavirus diarrhea in Tanzanian children, rotavirus diarrhea treatment and prevention strategies, and the effectiveness of rotavirus vaccines. It also lists countries that have introduced rotavirus vaccines into their national immunization programs.

Publication date: November 2012

Region: Africa

Part of series: Rotavirus disease and vaccines fact sheets

Publication date: 2004

Region: Africa

This document describes how project Optimize is collaborating with the Senegalese Ministry of Health to demonstrate innovations in the supply chain that can help to increase efficiency and improve performance, preparing the country for the introduction of new vaccines in the future.

Publication date: August 2012

Region: Global

This document presents formative research results from PATH's HPV Vaccines: Evidence for Impact project in India. PATH is working with ministries of health and other country partners to develop strategies for introducing vaccines against human papillomavirus (HPV), the primary cause of cervical cancer.

Publication date: March 2009

Region: Asia

This document presents new research results from PATH's HPV Vaccines: Evidence for Impact project in Peru. PATH is working with ministries of health and other country partners to develop strategies for introducing vaccines against human papillomavirus (HPV), the primary cause of cervical cancer.

Publication date: March 2009

Region: Latin America

This document presents new research results from PATH's HPV Vaccines: Evidence for Impact project in Uganda. PATH is working with ministries of health and other country partners to develop strategies for introducing vaccines against human papillomavirus (HPV), the primary cause of cervical cancer.

Publication date: March 2009

Region: Africa

This document presents formative research results from PATH's HPV Vaccines: Evidence for Impact project in Vietnam. PATH is working with ministries of health and other country partners to develop strategies for introducing vaccines against human papillomavirus (HPV), the primary cause of cervical cancer.

Publication date: March 2009

Region: Asia

In collaboration with experts from the World Health Organization (WHO), UNICEF, the Clinton Health Access Initiative, the University of Washington, and the national immunization programs of Uganda, Kenya, and Malawi, PATH developed the Cold Chain Equipment Manager (CCEM)—an inventory and planning tool that utilizes Microsoft Access–based software and analytic tools to help with data collection and analysis. Planning algorithms, data visualization, system modeling, and report-generation by CCEM adhere to national immunization policies and WHO/UNICEF standards. This poster, first presented in March 2012 at the Fifth Annual International Conference on Information Communication Technologies and Development, outlines the role and potential positive impact of the CCEM in lead up to the introduction of new pneumococcal and rotavirus vaccines.

Author: Anderson R, Lloyd J, Newland S

Publication date: March 2012

Region: Global