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Total results with these characteristics: 104

Subject: Health technologies > Diagnostic technologies

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Molecular Diagnostics Component Processes

A visual chart of the components of molecular diagnostics, using non-instrument and instrumented processing and signal detection. Presented at: PATH, December 1, 2009; Seattle, WA.

Author: Weigl B, LaBarre P

Publication date: December 2009

Region: Global

A New HPV-DNA Test for Developing Countries

Demonstration of a new 48-well HPV DNA batch test showing analytical sensitivity to 5000 copies of HPV DNA and other test characteristics that may be suitable for use in low-resource settings. Presented at: 22nd International Papillomavirus Conference, April 30, 2005; Vancouver, BC.

Author: Eder P, Nazarenko I, Peck R, Weigl B, Sellors J, Lorincz A

Publication date: May 2005

Region: Global

A New Immunochromatographic Strip Test for Neisseria Gonorrhoeae

The development of a rapid and simple immunochromatographic strip test using the L7/L12 Neisseria gonorrhoeae, testing using clinical samples. Presented at: 15th Biennial Congress, International Society of Sexually Transmitted Diseases Research, July 27, 2003; Ottawa, Canada.

Author: Matsyshen D, Svanas G, Maynard J, Tam M, Burgess Hay DC

Publication date: July 2003

Region: Global

New, Molecular Cervical Cancer Screening Technologies: Results From PATH's START-UP Project

This brief describes two human papillomavirus (HPV) screening methods developed and tested by PATH for low-resource settings: the careHPV™ DNA test and the OncoE6™ cervical test.

Author: PATH

Publication date: April 2013

Region: Global

The Nicaraguan Health System: An Overview of Critical Challenges and Opportunities

This report provides an overview of Nicaragua's health system and diagnostic needs. It is supported by individual case studies on Chagas disease, dengue, and malaria in Nicaragua. These studies focus on several factors influencing the health care system in Nicaragua, including recent trends, regional and national control strategies, financing and partnerships, and the unmet clinical needs associated with each illness.

Author: Sequeira M, Espinoza H, Amador JJ, Domingo G, Quintanilla M, de los Santos T

Publication date: February 2011

Region: Latin America

Non-Instrumented Isothermal Nucleic Acid Amplification Device

Part of the Technology Updates series, this fact sheet describes PATH's work to develop technologies that facilitate electricity-free, instrument-free nucleic acid amplification.

Publication date: November 2013

Region: Global

Part of series: Technology Updates

Non-Instrumented Nucleic Acid Amplification

A report on selecting and testing phase change materials for their ability to maintain a temperature range for duration sufficient to drive a PCR reaction.  Presented at: Microfluidics, BioMEMS, and Medical Microsystems VI, January 22, 2008; San Jose, CA.

Author: Tang D, LaBarre P, Weigl BH, Stayton PS

Publication date: January 2008

Region: Global

Non-Instrumented Nucleic Acid Amplification (NINA): Instrument-Free Molecular Diagnostics for Low-Resource Settings

PATH has demonstrated the use of CaO for heat and a proprietary engineered phase change material (EPCM) to maintain an assay mixture within a narrow temperature range suitable for isothermal amplification. We are currently working to develop, integrate, and validate components of this NAAT kit. Presented at: AACC 42nd Annual Oak Ridge Conference, April 22, 2010; San Jose, CA.

Author: LaBarre P, Beddoe A, Gerlach J, et al

Publication date: April 2010

Region: Global

A Novel and Sensitive Rapid Diagnostic Test for Chagas Disease

The PATH-Lemos Chagas rapid test has great potential as a highly sensitive diagnostic test for Chagas disease, suitable for use at the point-of-care.  Presented at: AACC 42nd Annual Oak Ridge Conference, April 22, 2010; San Jose, CA.

Author: Barfield CA, Barney RS, Crudder CH, et al

Publication date: April 2010

Region: Global

Overview of Nucleic Acid–Based Diagnostic Techniques

To support a World Health Organization (WHO) Evidence Review Group on Malaria Diagnostics in Low-Transmission Settings in December 2013, PATH was invited to provide an overview of polymerase chain reaction and isothermal molecular methods for malaria infection detection. The PowerPoint is provided here and the WHO policy recommendations from the evidence review can be found here.

Author: LaBarre P, Tietje K

Publication date: December 2013

Region: Global

PATH in China: Joining With Diverse Partners to Create Sustainable Health Solutions

This brochure outlines PATH's work in China, with emphasis on public-private partnerships for product development. Areas of focus include vaccines and immunization, health technologies, and women's health.

Publication date: November 2012

Region: Asia

PATH Today (Fall 1998)

Publication date: September 1998

Region: Global

Part of series: PATH Today

PATH Today (Fall 2002)

Publication date: September 2002

Region: Global

Part of series: PATH Today

PATH Today (Fall 2010)

This issue of PATH Today highlights new, innovative technologies coming from the lab and shop at PATH, a spotlight on the December launch of the meningitis vaccine in Western Africa, and a tuberculosis project in Tanzania. Also noted is the 1+1 Challenge, expanding PATH’s presence with new country offices in Africa, and the announcement of a new leader for PATH's India country program.

Publication date: October 2010

Region: Global

Part of series: PATH Today

PATH Today (Fall 2011)

This edition of PATH Today features our work to protect children from diarrheal disease, the use of mobile devices to diagnose tuberculosis and improve maternal health, and a profile of PATH donor Ann Hayes. The issue also provides information about our yearly reports to donors, workplace and planned giving, and the results of the meningitis vaccine campaign launch in sub-Saharan Africa.

Publication date: September 2011

Region: Global

Part of series: PATH Today

PATH Today (Spring 2006)

This edition of PATH Today features the articles "A laboratory on a card," "Using microfluidic tests to identify infection," and "Common proteins for common prevention," which highlights the work of John Boslego and his team on pneumococcus. It also includes a letter from donor Shannon Scopa about her family's ordeal with rotavirus.

Publication date: May 2006

Region: Global

Part of series: PATH Today

PATH Today (Winter 1998)

Publication date: December 1998

Region: Global

Part of series: PATH Today

PATH's Work in Tuberculosis: Collaborating on Innovative and Sustainable Solutions for a TB-Free World

Since 2001, PATH has brought our global health expertise and innovative approaches to the fight against tuberculosis. We work hand in hand with global partners with a special focus on high-burden countries.

Publication date: September 2013

Region: Global

Preventing and Managing Noncommunicable Diseases

This fact sheet provides an overview of PATH’s work in noncommunicable diseases (NCDs). Our goal is to reduce preventable morbidity and mortality by using innovation and technology to increase access to prevention and care for NCDs in low-resource settings.

Publication date: April 2014

Region: Global

Preventing the Spread of TB: Improving Infection Prevention and Control in India’s Health Facilities

This project brief describes one aspect of PATH’s contributions to tuberculosis (TB) control in India. With the support of the United States Agency for International Development, PATH worked with India’s Revised National TB Control Program to implement new national guidelines on airborne infection control in India. Work included developing education materials for health workers and their patients, convening experience-sharing workshops for national TB program staff, and training local engineers and architects to design effective infection-control measures within health facilities.

Publication date: May 2014

Region: Asia

Part of series: Tuberculosis activities in India

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