This booklet presents advocacy tips, success stories, and examples of efforts to bridge the worlds of science and policymaking and to help ensure that policymakers at national, regional, and international levels have the information needed to make timely and informed decisions as soon as a first malaria vaccine becomes available for use.

Publication date: February 2012

Region: Africa

This poster summarizes PATH’s recent activities as part of a consortium lead by the University of Washington to develop the DxBox, a system comprising a portable instrument and low-cost disposable cards. The prototype is being developed to diagnose typhoid fever, dengue fever, rickettsial diseases, malaria, measles, and influenza. PATH’s contributions are immunoassay development, field studies, and user needs assessment. Presented at The American Society of Tropical Medicine and Hygiene (ASTMH), November 12, 2006; Atlanta, GA.

Author: Gerlach JL, Singhal MC, Watts K, et al

Publication date: November 2006

Region: Global

The PATH Malaria Vaccine Initiative commissioned this analysis to begin elucidating the World Health Organization (WHO) process for developing policy guidelines for a malaria vaccine. The analysis considered past WHO recommendations on new interventions and assessed potential implications for a malaria vaccine.

Author: Milstien J, Brooks A, Cardenas V, Cheyne J

Publication date: May 2008

Region: Global

This report in the Roll Back Malaria Progress & Impact Series examines how private-sector investment in malaria control has improved cost-effectiveness at companies operating in malaria-endemic regions in Africa.

Author: Mouzin E, Sedlmayr R, Miller J, et al

Publication date: May 2011

Region: Africa

Part of series: Roll Back Malaria Progress & Impact Series

Clinical trials are a critical source of data for decisions around vaccine development. This fact sheet provides information about the phases of clinical trials.

Publication date: October 2009

Region: Global

PATH developed this manual for community health workers to facilitate and support the implementation of the AIDS, Population, and Health Integrated Assistance (APHIA) II project’s community-based activities in Eastern, Nyanza, and Western provinces of Kenya. The manual was developed with funding from the US Agency for International Development. It is available as one large file or as 17 smaller files.

Publication date: July 2007

Region: Africa

Malaria is a leading cause of morbidity and mortality in children younger than five years in Kenya. Within the context of planning for a vaccine to be used alongside existing malaria control methods, this study, published in Malaria Journal, explores sociocultural and health communications issues among individuals who are responsible for or influence decisions on childhood vaccination at the community level.

Author: Ojakaa DI, Ofware P, Machira YW, et al

Publication date: May 2011

Region: Africa

This paper describes research into the anticipated processes and data needed to inform decision-making on malaria vaccines, the most advanced of which is still in phase 3 trials.

Author: Brooks A, Ba-Nguz A

Publication date: February 2012

Region: Africa

Part of the Roll Back Malaria Progress & Impact Series, this report demonstrates the dramatic successes achieved by the malaria community over the past ten years. As a result of greater commitment and increased resources being made available to national malaria control programs, interventions have reached vulnerable populations and thousands of lives have been saved. The report details the evolution and effectiveness of the Roll Back Malaria Partnership over the years, demonstrating how a strong, well-organized community can help deliver broad health benefits while relieving overburdened health systems.

Author: White Johansson EW, Newby H, Carvajal L, et al

Publication date: September 2011

Region: Global

Part of series: Roll Back Malaria Progress & Impact Series

This fact sheet provides an overview of PATH's work in Zambia, including our work to support data-driven malaria control measures, improve child health and nutrition, prevent HIV infection, and create better information management systems.

Publication date: December 2011

Region: Africa

This poster presents a study to collect and characterize specimens from febrile patients who were suspected to have malaria, pedigree specimens against a panel of nucleic acid and serological markers, and draw early insights into data that would be generated by a multiplex diagnostic platform. Presented at The American Society of Tropical Medicine and Hygiene, December 7, 2008; New Orleans, LA.

Author: Gerlach JL, Waitumbi J, Koros J, et al

Publication date: December 2008

Region: Global

A report on the selection and evaluation of target markers for a multiplex diagnostic platform under development. Based on the DxBox platform being developed as part of a public-private consortium lead by the University of Washington. Presented at the Molecular Medicine Tri-Conference, March 25, 2008; San Francisco, CA.

Author: Gerlach JL, Anyona S, Koros J, et al

Publication date: March 2008

Region: Global

This fact sheet describes PATH's drug development program, including our work to develop new treatments for malaria, kala-azar (visceral leishmaniasis), and diarrheal disease.

Publication date: September 2012

Region: Global

Part of series: PATH's areas of focus fact sheets

This study evaluated the performance of PATH’s rapid diagnostic assay detecting histidine rich protein 2 (HRP-2) antigen when used by local health care providers in a rural field setting in Lao PDR and examined rapid diagnostic assays as a strategy to identify participants for in vivo treatment trials in a rural field site.

Author: Labbé AC, Pillai DR, Hongvangthong B, et al

Publication date: January 1999

Region: Global

The January 2004 issue of PATH's programmatic newsletter focuses on five projects: preventing HIV and AIDS in the Philippines, evaluating a malaria vaccine candidate, increasing youth access to services through pharmacies, advancing the Ultra Rice technology, and using theater to encourage social change.

Publication date: January 2004

Region: Global

Part of series: Directions in Global Health

This special issue of Directions in Global Health features PATH's work in malaria prevention and control. It describes PATH's partnerships, experience in Zambia, clinical trial activities, efforts to prepare for vaccine introduction, and advocacy efforts.

Author: PATH

Publication date: May 2006

Region: Global

Part of series: Directions in Global Health

This special issue of Directions in Global Health highlights PATH's vaccine partnership efforts: PATH Malaria Vaccine Initiative (MVI), pneumococcal vaccine development project, Meningitis Vaccine Project, cervical cancer vaccine project, and Rotavirus Vaccine Program. The issue also features a case study of the vaccine vial monitor.

Author: PATH

Publication date: May 2007

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health describes PATH's work to control and prevent diarrheal disease, reach out to young scouts in Kenya and Uganda with HIV/AIDS information, assess the impact of malaria control efforts in Zambia, conduct DHS surveys, and shape HPV vaccine introduction in Peru.

Author: PATH

Publication date: December 2008

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health features PATH’s Sure Start project, which helped to improve maternal and newborn health in India. Other articles cover strategies to eliminate malaria, advocacy and communications to improve tuberculosis control, a landmark vaccine introduction in Ghana, and a new child-health initiative in southern Africa.

Publication date: May 2012

Region: Global

Part of series: Directions in Global Health

This website about PATH’s drug development program provides an overview of the program and its featured projects. See other PATH program websites.

Publication date: 2013

Region: Global

Part of series: PATH's program websites