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Subject: Vaccines and immunization > Diarrheal disease

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Directions in Global Health (Volume 5, Issue 3)

This issue of Directions in Global Health describes PATH's work to control and prevent diarrheal disease, reach out to young scouts in Kenya and Uganda with HIV/AIDS information, assess the impact of malaria control efforts in Zambia, conduct DHS surveys, and shape HPV vaccine introduction in Peru.

Author: PATH

Publication date: December 2008

Region: Global

Part of series: Directions in Global Health

Directions in Global Health (Volume 8, Issue 1)

This issue of Directions in Global Health features PATH’s work related to vaccines and immunization. Articles cover the development and introduction of a vaccine to eliminate epidemic meningitis in Africa, use of vaccines and other interventions to prevent cervical cancer, transformation of vaccine distribution systems, expansion of access to rotavirus vaccines, and advancements in vaccine technologies.

Publication date: May 2011

Region: Global

Part of series: Directions in Global Health

Directions in Global Health (Volume 9, Issue 1)

This issue of Directions in Global Health features PATH’s Sure Start project, which helped to improve maternal and newborn health in India. Other articles cover strategies to eliminate malaria, advocacy and communications to improve tuberculosis control, a landmark vaccine introduction in Ghana, and a new child-health initiative in southern Africa.

Publication date: May 2012

Region: Global

Part of series: Directions in Global Health

Dry-Reagent Storage for Disposable Lab-on-Card Diagnosis of Enteric Pathogens

An exploration of one technique for drying reagents onto a microfluidics card. Reagents needed for immunocapture, lysis, and PCR for pathogen capture can be stored in trehalose or trehalose dextran. Presented at the 1st Distributed Diagnosis and Home Healthcare Conference, April 2, 2006; Arlington, VA.

Author: Ramachandran S, Weigl BH, Gerdes JC, et al

Publication date: April 2006

Region: Global

Efficacy of Standard Methods for Water Testing at a Range of Nonstandard Temperature

Fifteen strains of Escherichia coli from various geographical areas, animal, and soil sources were tested on standard and nonstandard detection assays at temperatures from 23°C to 45°C to test the viability of currently available E. coli tests in low-resource settings. Presented at the American Society for Microbiology Conference, June 1, 2008; Boston, MA.

Author: Allen E, Dillman L, Weigl B

Publication date: June 2008

Region: Global

Exploring New, Non-replicating Rotavirus Vaccines

This fact sheet summarizes the technical efforts and objectives of PATH's non-replicating rotavirus vaccine (NRRV) project. It outlines the vaccine candidates under evaluation and primary partners, as well as the rationale for the NRRV approach.

Publication date: January 2013

Region: Global

Global Vaccine Action Plan: 2011-2020

The Global Vaccine Action Plan (GVAP)—endorsed by the 194 Member States of the World Health Assembly in May 2012—is a roadmap to prevent millions of deaths by 2020 through more equitable access to vaccines for people in all communities. The GVAP aims to strengthen routine immunization, introduce new and improved vaccines, and advance research and development for the next generation of vaccines and technologies.

Author: Decade of Vaccines Collaboration

Publication date: May 2012

Region: Global

Improving Health for Families Everywhere: PATH Reaches Mothers, Children, and Communities With Key Innovations for Strong Futures

PATH has worked to improve maternal and child health, nutrition, and family planning in developing countries for more than 30 years. This brochure describes our integrated approach to reach mothers, children, and communities with key innovations for strong futures.

Publication date: May 2010

Region: Global

Increasing Access to Lifesaving Vaccines: PATH Closes the Immunization Gap Through Innovation and Collaboration

This fact sheet outlines PATH's work on vaccines and immunization. Topic areas include developing affordable vaccines, designing innovative vaccine technologies, and expanding uptake of existing vaccines. These efforts reduce the burden of malaria, meningitis, diarrheal disease, Japanese encephalitis, pneumococcal disease, influenza, rotavirus, polio, respiratory syncytial virus (RSV), and other infectious diseases in developing countries.

Publication date: December 2013

Region: Global

Part of series: Areas of focus fact sheets

India Country Program Website

This website about PATH’s India country program provides an overview of the program and its featured projects. See other PATH program websites.

Publication date: 2014

Region: Asia

Part of series: Program websites

Innovation in Enteric Vaccine Development: Addressing Bacterial Causes of Diarrhea

This fact sheet describes PATH's enteric vaccine project from a technical perspective. It includes an overview of PATH's vaccine development portfolio, research activities, and partners to support the development of effective and affordable vaccines against Shigella and enterotoxigenic Escherichia coli, the leading bacterial causes of diarrhea, for children in the developing world.

Publication date: October 2013

Region: Global

Part of series: Diarrheal disease fact sheets

An Integrated Approach to Confronting Diarrheal Disease

This briefing paper provides an overview of the tools and interventions involved with an integrated approach to diarrheal disease control, including vaccines, oral rehydration, breastfeeding, and zinc treatment. The document also advocates for renewed commitment at global, regional, and national levels.

Publication date: July 2011

Region: Global

Part of series: Diarrheal disease fact sheets

Integrating Diarrheal Disease and Pneumonia Control

This fact sheet describes PATH's integrated approach to tackling diarrheal disease and pneumonia, two of the leading killers of young children. This approach emphasizes overlapping protection, the scale-up of proven methods, and the development of innovative new tools including diagnostics, drugs, and vaccines.

Publication date: December 2013

Region: Global

Part of series: Areas of focus fact sheets

Introduction of Rotavirus Vaccine with Support from the GAVI Alliance: Information to Assist the National Decision-Making and Application Process

This guide summarizes considerations for rotavirus vaccine introduction in Eastern European countries eligible for support from the GAVI Alliance.

Publication date: December 2007

Region: Eastern Europe

Key Facts About Rotavirus Disease and Vaccines

Publication date: 2006

Region: Global

Lab-on-a-Card Assay for Enteric Pathogens

We describe the functional elements of a diagnostic instrument and disposable enteric card system under development that rapidly identifies and differentiates Shigella, E. coli, Campylobacter, and Salmonella in stool samples. These elements, currently realized as microfluidic subcircuits on individual cards, are: (1) pathogen capture and lysing, (2) nucleic acid capture, (3) on-chip rapid PCR, and (4) lateral flow detection of amplicons. Presented at the Solid State Sensor, Actuator and Microsystems Workshop, June 4, 2006; Hilton Head Island, SC.

Author: Weigl BH, Gerdes JC, Tarr P, et al

Publication date: June 2006

Region: Global

Oral Rehydration Therapy/Oral Rehydration Solution

This fact sheet aims to raise awareness about oral rehydration therapy to rehydrate people—particularly infants and children—who have lost fluids because of diarrhea. One in a set of introductory resources, it provides stakeholders and policymakers in the world’s poorest countries with crucial information on a proven intervention in the fight against diarrheal disease.

Publication date: May 2013

Region: Global

Part of series: Diarrheal disease fact sheets

Outsourcing the Vaccine Supply Chain and Logistics System to the Private Sector: The Western Cape Experience in South Africa

Facilitated by project Optimize, a World Health Organization and PATH collaboration, this review was conducted in the Western Cape of South Africa whereby the Biovac Institute (a third-party, private-sector company) took over the roles of vaccine procurement, warehouse management, inventory management, and vaccine distribution directly to health centers.

Author: Lydon P

Publication date: October 2011

Region: Africa

PATH in China: Joining With Diverse Partners to Create Sustainable Health Solutions

This brochure outlines PATH's work in China, with emphasis on public-private partnerships for product development. Areas of focus include vaccines and immunization, health technologies, and women's health.

Publication date: November 2012

Region: Asia

PATH in India: Harnessing Innovation to Improve Health in India and Around the World

This brochure outlines PATH's work in India, where we're addressing a range of health problems while leveraging the country’s growing capacity to innovate and contribute to global health solutions.

Publication date: December 2013

Region: Global

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