This overview describes how PATH has developed a low-cost and straightforward technology for protecting aluminum-adjuvanted liquid vaccines from the irreversible damage that results from freezing. Many current vaccines of importance to global health contain an aluminum salt adjuvant or its equivalent (such as aluminum hydroxide, aluminum phosphate, or calcium phosphate) and would benefit from the technology.

Publication date: October 2012

Region: Global

This fact sheet provides an overview of PATH's work in protecting children from diarrheal disease.

Publication date: September 2012

Region: Global

Part of series: PATH's areas of focus fact sheets

This document is part of a series that describes the serious risk of freezing vaccines and provides tools to reduce freezing in the cold chain. The materials contain current WHO-recommended freeze-prevention strategies targeted toward all levels of storage and transport of vaccines.

Publication date: 2003

Region: Global

This policy report highlights the essential role that public-private partnerships play in driving global health product development and offers insights into the key components of successful multi-sector partnerships led by PATH. For examples of our European public-private partnerships, see Public-Private Partnerships for Global Health: PATH's Collaborations With European Partners.

Publication date: March 2013

Region: Global

The Optimize project, a collaboration between PATH and the World Health Organization, commissioned this white paper to examine the issues influencing vaccine producer willingness to advance, adopt, and commercialize value-added technologies for vaccines for low-income and lower-middle-income country markets.

Author: Gilchrist S

Publication date: November 2009

Region: Global

This national-level quantification tool can be used to develop estimated needs for newborn resuscitation devices. It is designed only to provide estimates of product quantities for planning and cost simulations and is not intended for planning detailed distribution. There are two Excel-based formats of the tool: The enhanced format includes simple design elements, such as graphics and navigation arrows, to guide users through the tool. The standard format retains the cell-based formatting of a traditional Excel file. Both versions contain the same information and formulas and will yield the same data. We invite users to choose the presentation that best meets their needs.

Publication date: February 2014

Region: Global

This document is intended to start discussions around quantifying the need for safe injection equipment and the amount of infectious sharps waste produced by testing and treatment programs for diseases such as HIV/AIDS, tuberculosis, and malaria. The analysis was developed to support advocacy efforts to integrate injection safety as an essential element of all health care programs.

Publication date: June 2009

Region: Global

This four-page brochure tells the story of the Uniject device--how it grew from a concept to an easy-to-use, all-in-one injection device that will be used to vaccinate every newborn in Indonesia against hepatitis B and to help eliminate maternal and neonatal tetanus globally. The publication covers the development, evaluation, licensing, production, and design and function of Uniject. Photographs and a timeline of Uniject's history included.

Author: E.Simpson

Publication date: 2003

Region: Global

The global diabetes epidemic impacts pregnant women and their babies. This poster describes a rapid, low-cost, non-fasting screening assay proposed by PATH to be used at antenatal care visits. The test would enable interventions to prevent or delay diabetes in the mother and child.

Publication date: July 2012

Region: Global

Part of the Technology Updates series, this fact sheet describes PATH's work to develop a rapid, easy-to-read, low-cost test for malaria.

Publication date: May 2009

Region: Global

Part of series: Technology Updates

Part of the Technology Updates series, this fact sheet describes PATH's work to develop rapid tests for cervical cancer.

Publication date: July 2013

Region: Global

Part of series: Technology Updates

This guide introduces the retinol binding protein enzyme immunoassay (RBP-EIA) to potential advocates and users, and provides information about its prospective role in public health.

Author: Hix J; Levin C; Gorstein J

Publication date: 2003

Region: Global

This document serves as a guide to phlebotomists and a training aid in the proper methods of obtaining blood samples for analysis by the retinol-binding protein enzyme immunoassay (RBP-EIA) used in testing for vitamin A deficiency.

Publication date: 2005

Region: Global

This document summarizes available evidence for the validation and establishment of a rapid, field-based tool for the assessment of vitamin A deficiency using the retinol-binding protein immunoassay (RBP-EIA) test.

Publication date: 2006

Region: Global

This job aid illustrates how to read time-temperature indicators with the Uniject™ injection system.

Publication date: August 2011

Region: Global

This worksheet can be used during trainings to help health workers learn how to read time-temperature indicators with the Uniject™ injection system.

Publication date: August 2011

Region: Global

This Alliance for Cervical Cancer Prevention fact sheet summarizes evidence published since 2009 on cervical cancer screening approaches for low-resource settings.

Publication date: May 2011

Region: Global

Part of the Technology Updates series, this fact sheet describes PATH's work on single-dose, prefilled reconstitution devices (SPRDs). SPRDs can make reconstitution of critical vaccines safer and more economical and can help eliminate adverse events or wastage that can occur with improper reconstitution, which also reduces impact on the medical waste disposal system.

Publication date: May 2012

Region: Global

Part of series: Technology Updates

The study was undertaken to evaluate the acceptability and ease of use of the Uniject prefilled, single-use injection device by midwives at primary and secondary level facilities, the effectiveness of active management of the third stage of labor (AMTSL) in reducing rates of post partum hemorrhage (PPH) and the need for hemorrhage treatments, the cost-effectiveness of routine delivery of AMTSL, and the relative costs of using oxytocin in ampoules or in Uniject. The study was conducted in six districts of Thanh Hoa province from June to December 2004.

Publication date: 2003

Region: Asia

Project Optimize, a collaboration between the World Health Organization and PATH, aims to provide national immunization programs with recommendations to build integrated health supply systems, including strategic linkages with the parastatal and private sector. Ultimately, integration will allow public health programs to reduce uncertainties and risks, achieve economies of scale, shorten delivery lead times, improve procurement, provide better incentives for health workers, and improve quality of service to clients.

Publication date: July 2012

Region: Global