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Browse PATH publications
Subject: Health technologies > Vaccine delivery
- Innovation for Global Health
Innovation for Global Health is the Global Health Technologies Coalition's e-newsletter focusing on the development and delivery of lifesaving health tools to people in need worldwide. The newsletter provides updates on the latest research and policy developments on innovative tools to prevent, diagnose, and treat diseases. It includes news from US agencies, Congress, the current administration, and the global health community at large.
Publication date: 2013
Region: North America and Europe
Part of series: E-newsletters
- Installing and Testing Battery-Free Solar Refrigerators in Vietnam
This photo set contains photographs by project Optimize of the installation and initial testing of two battery-free solar refrigerators in May 2011 in Vietnam.
Publication date: April 2013
Region: Asia
Part of series: Project Optimize photo sets
- An Integrated Approach to Health Information Systems in Guatemala
This project Optimize document describes an effort by the World Health Organization, PATH, the Pan American Health Organization, and the Guatemala Ministry of Public Health and Social Services to address challenges related to vaccine introduction. The goal is to develop an information system that will enable the digital recording and transmission of immunization data.
Publication date: November 2010
Region: Global
- Intradermal Adapter
Part of the Technology Updates series, this fact sheet describes PATH's work on an intradermal adapter, which makes it easier to administer intradermal injections.
Publication date: April 2012
Region: Global
Part of series: Technology Updates
- Intradermal Delivery of Vaccines: A Review of the Literature and the Potential for Development for Use in Low- and Middle-Income Countries
Produced by project Optimize and the vaccine technologies team at PATH, this report: (1) summarizes the clinical evidence supporting the intradermal route for vaccine administration and the devices being developed for this purpose; (2) determines whether intradermal delivery broadly holds promise for vaccine applications for low- and middle-income countries in the future; and (3) begins to prioritize vaccine targets and device strategies that best fit the public health needs in these countries and likely merit further investigation. The document is available as one large file or as four smaller files for easier downloading.
Publication date: August 2009
Region: Global
- Intranasal Delivery Devices
Part of the Technology Updates series, this fact sheet describes PATH's work on intranasal delivery devices to administer vaccines.
Publication date: October 2011
Region: Global
Part of series: Technology Updates
- Introduction of Rotavirus Vaccine with Support from the GAVI Alliance: Information to Assist the National Decision-Making and Application Process
This guide summarizes considerations for rotavirus vaccine introduction in Eastern European countries eligible for support from the GAVI Alliance.
Publication date: December 2007
Region: Eastern Europe
- Investing in Stronger Vaccine Supply Chains: Reaching Children With Immunization, Saving Lives
This brochure describes how advances in vaccine supply chain systems can accelerate the delivery of lifesaving immunizations to people who need them. The document offers recommendations for global policymakers to support countries in building more effective supply chain systems.
Publication date: September 2012
Region: Global
- Keeping Track of Vietnam's Vaccines
Project Optimize, a collaboration between the World Health Organization and PATH, is helping national immunization programs prepare for the future. This evidence brief describes how project Optimize worked in Vietnam with national, regional, and local partners to help introduce VaxTrak, a software program that allows users at various levels of the health system to track vaccine stock and report monthly immunization activity.
Publication date: October 2012
Region: Asia
- Landscape Analysis: Analysis of EVSM Indicators
The Effective Vaccine Stores Management (EVSM) assessment tool was created to help countries and agencies evaluate critical components of the country’s primary vaccine store. To date, 57 countries have completed the EVSM assessment. This project Optimize report evaluates 42 EVSM assessment spreadsheets.
Publication date: June 2008
Region: Global
- Landscape Analysis: Cool Chain Technologies
Technologies related to the temperature control of vaccines during the distribution process are essential to the cool chain. This project Optimize report provides a landscape analysis of these technologies and their appropriateness for use with vaccines in the developing world.
Publication date: June 2008
Region: Global
- Landscape Analysis: Trends in Vaccine Availability and Novel Vaccine Delivery Technologies: 2008–2025
This project Optimize landscape analysis identifies trends in the availability of vaccines and novel vaccine delivery technologies that are and will be of relevance to low- and middle-income countries from present through 2025. The document is available as one large file or as three smaller sections for easier downloading.
Publication date: July 2008
Region: Global
- Malaria Vaccine Technology Roadmap
Scientists have been working for decades to develop a preventive malaria vaccine. While they have successfully demonstrated that such a vaccine is possible, many challenges continue to impede progress on the road to an effective malaria vaccine. As a result, the Malaria Vaccine Advisory Committee to the World Health Organization (WHO), coordinated by the WHO Initiative for Vaccine Research, called for a collective effort to explore and address the challenges. This effort resulted in the Malaria Vaccine Technology Roadmap process.
Publication date: August 2006
Region: Global
- Meeting Requirements for Controlled Room Temperature Storage of Medicines
Project Optimize and the Tunisian Ministry of Public Health are collaborating to explore new logistics and supply chain solutions that can optimize the vaccine supply chain. This report describes a study that project Optimize commissioned to assess the least-cost, most energy-efficient solution for pharmaceutical stores at the regional and district level.
Author: Lloyd J, McCarney S
Publication date: October 2012
Region: Africa
- Microneedle Patches
Part of the Technology Updates series, this fact sheet describes PATH's work, in collaboration with the Georgia Institute of Technology and Emory University, to evaluate and create a microneedle patch that will allow people to self-administer influenza vaccine.
Publication date: April 2012
Region: Global
Part of series: Technology Updates
- Monitoring Ambient and Cold Chain Temperatures During Delivery of Human Papillomavirus Vaccine in Vietnam and Uganda: Summary Report
As part of project Optimize, a five-year human papillomavirus (HPV) vaccine demonstration project is under way in Vietnam, Uganda, India, and Peru to generate evidence for government decision-making about successful vaccine delivery strategies to provide HPV vaccine to young adolescent girls. HPV vaccine is a strong candidate for storage and transport in a controlled temperature chain at temperatures higher than the standard 2° to 8°C cold chain storage.
Publication date: September 2010
Region: Global
- Monitoring Ambient Temperatures Experienced During Delivery of Human Papillomavirus Vaccine in Uganda
As part of project Optimize, a five-year human papillomavirus (HPV) vaccine demonstration project is under way in Uganda and three other countries to demonstrate how existing health systems can be adapted to successfully provide HPV vaccine to young adolescent girls. HPV vaccine is a strong candidate for storage and transport in a controlled temperature chain at temperatures higher than the standard 2º to 8ºC cold chain storage.
Author: Robertson J, Mugisha E, Kumakech E, LaMontagne D, Janmohamed A, Kristensen D, Seruyange R, Bamwine J, Ssekito G, Newland S
Publication date: April 2010
Region: Global
- A Moving Warehouse Delivers Vaccines and Essential Health Supplies in Senegal
In March 2011, the government of Senegal began using a "moving warehouse" to transport vaccines and vaccine supplies from regional stores directly to district stores and health posts on a monthly basis in the Saint-Louis region. This photo set explains how the moving warehouse works and shares results from a project Optimize–supported pilot demonstration of the moving warehouse from 2010 to 2012.
Publication date: April 2013
Region: Africa
Part of series: Project Optimize photo sets
- A Moving Warehouse in Senegal
As part of the project Optimize traveling exhibit, this banner illustrates the concept of integrating vaccines with other health products in streamlined supply chains. It highlights Senegal’s “moving warehouse,” which was introduced to offer a better system of distribution down the chain. Rather than having health facilities collect vaccines and supplies, the moving warehouse delivery teams visit each facility, check inventory, and replenish stock as needed. Each team includes a supervisor and cold chain technician who provide supportive supervision to health care workers and ensure that equipment is operating correctly.
Publication date: April 2013
Region: Global
Part of series: Supply Systems for Today and Tomorrow: Project Optimize traveling exhibit
- Mucosal Immunization Technologies
Part of the Technology Updates series, this fact sheet describes PATH's work on mucosal immunization technologies.
Publication date: May 2012
Region: Global
Part of series: Technology Updates

