Project Optimize, a collaboration between the World Health Organization and PATH, is helping national immunization programs prepare for the future. This evidence brief describes how project Optimize worked in Vietnam with national, regional, and local partners to help introduce VaxTrak, a software program that allows users at various levels of the health system to track vaccine stock and report monthly immunization activity.

Publication date: October 2012

Region: Asia

Publication date: 2006

Region: Global

This short film shows how simple screening tests and community mobilization are saving lives across India. And how Costa Rican scientists—and young female volunteers—are helping us understand the exciting potential of a new vaccine against human papillomavirus.

Publication date: 2004

Region: Global

Part of series: Kill or Cure? videos

The film provides a glimpse of the serious Japanese encephalitis outbreak in India in 2005, along with innovative diagnostic work in Malaysia, and it explains why vaccination is the only effective way to control the disease.

Publication date: 2005

Region: Asia

Part of series: Kill or Cure? videos

Filmed during the 2007 epidemic in Burkina Faso, the documentary offers a poignant and revealing account of the devastating impact meningitis epidemics have on individuals and communities. The film also takes viewers to Mali, where the Meningitis Vaccine Project (a collaboration between PATH and the World Health Organization) and the Serum Institute of India Limited are testing a new vaccine that offers hope for eliminating epidemics as a public health problem in sub-Saharan Africa.

Publication date: 2007

Region: Africa

Part of series: Kill or Cure? videos

This film in the BBC World’s Kill or Cure? series uncovers the challenges of preventing and treating cervical cancer in Africa and highlights exciting new opportunities for dramatically reducing the toll of disease. The BBC crew follows Sarah Nyombi—Ugandan member of parliament, trained midwife, and women's health advocate—as she explores the landscape of cervical cancer. The film is available in two versions: 25 minutes and 12 minutes.

Publication date: July 2009

Region: Global

Part of series: Kill or Cure? videos

We describe the functional elements of a diagnostic instrument and disposable enteric card system under development that rapidly identifies and differentiates Shigella, E. coli, Campylobacter, and Salmonella in stool samples. These elements, currently realized as microfluidic subcircuits on individual cards, are: (1) pathogen capture and lysing, (2) nucleic acid capture, (3) on-chip rapid PCR, and (4) lateral flow detection of amplicons. Presented at the Solid State Sensor, Actuator and Microsystems Workshop, June 4, 2006; Hilton Head Island, SC.

Author: Weigl BH, Gerdes JC, Tarr P, et al

Publication date: June 2006

Region: Global

The Effective Vaccine Stores Management (EVSM) assessment tool was created to help countries and agencies evaluate critical components of the country’s primary vaccine store. To date, 57 countries have completed the EVSM assessment. This project Optimize report evaluates 42 EVSM assessment spreadsheets.

Publication date: June 2008

Region: Global

Technologies related to the temperature control of vaccines during the distribution process are essential to the cool chain. This project Optimize report provides a landscape analysis of these technologies and their appropriateness for use with vaccines in the developing world.

Publication date: June 2008

Region: Global

This project Optimize landscape analysis identifies trends in the availability of vaccines and novel vaccine delivery technologies that are and will be of relevance to low- and middle-income countries from present through 2025. The document is available as one large file or as three smaller sections for easier downloading.

Publication date: July 2008

Region: Global

This document summarizes the results of a study among children in the Philippines who received both measles and Japanese encephalitis vaccines at nine months of age. Data for this follow-up study were collected one year post-vaccination.

Author: Gatchalian S, Jacobson J, Kelly K, Sutee Y, Yaïch M, Yao Y, Zhang L, Zhou B

Publication date: November 2007

Region: Asia

Financing the human papillomavirus (HPV) vaccine and mobilizing resources to support new delivery mechanisms will constitute some of the most significant challenges to achieving widespread HPV vaccination in the developing world. This brief summarizes the main findings of the longer research publication, HPV Vaccine Adoption in Developing Countries: Cost and Financing Issues.

Publication date: December 2007

Region: Global

Author: Hooks C; Joseph L

Publication date: 2004

Region: Global

This website about PATH’s Malaria Vaccine Initiative (MVI) global program provides an overview of the program and its featured projects. See other PATH program websites.

Publication date: 2013

Region: Global

Part of series: PATH's program websites

Launched in 2002, this website provides information on the Malaria Vaccine Initiative at PATH.

Publication date: 2013

Region: Global

Part of series: Websites

Publication date: 2001

Region: Global

Scientists have been working for decades to develop a preventive malaria vaccine. While they have successfully demonstrated that such a vaccine is possible, many challenges continue to impede progress on the road to an effective malaria vaccine. As a result, the Malaria Vaccine Advisory Committee to the World Health Organization (WHO), coordinated by the WHO Initiative for Vaccine Research, called for a collective effort to explore and address the challenges. This effort resulted in the Malaria Vaccine Technology Roadmap process.

Publication date: August 2006

Region: Global

Publication date: 2004

Region: Global

This study by PATH's Japanese encephalitis (JE) project evaluated whether measles vaccine and the live, attenuated JE vaccine can be safely co-administered with no effect on the immunogenicity of either.

Author: Gatchalian S, Jacobson J, Kelly K, Sutee Y, Yaïch M, Yao Y, Zhang L, Zhou B

Publication date: December 2006

Region: Asia

Project Optimize and the Tunisian Ministry of Public Health are collaborating to explore new logistics and supply chain solutions that can optimize the vaccine supply chain. This report describes a study that project Optimize commissioned to assess the least-cost, most energy-efficient solution for pharmaceutical stores at the regional and district level.

Author: Lloyd J, McCarney S

Publication date: October 2012

Region: Africa