This special issue of Directions in Global Health highlights PATH’s work to advance technologies to improve global health. Featured technologies include low-cost tests to screen for cervical cancer, a new vaccine to protect against meningitis in Africa, products to prevent diarrheal disease, and Ultra Rice food fortification technology. The issue also includes a summary of PATH’s approach to developing and introducing innovative health technologies.

Publication date: May 2009

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health showcases PATH’s global presence. It highlights work related to influenza in Africa, HIV and AIDS in Eastern Europe,  Japanese encephalitis in Asia, gender-based violence in Latin America and the Caribbean, and diagnostic technologies in North America. The back cover features a map and summary information on PATH’s work around the world.

Publication date: August 2009

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health features PATH’s work to optimize vaccine supply systems, advance development of malaria vaccine candidates, prevent postpartum hemorrhage to save mothers’ lives, address health needs in Tanzania, and use monitoring and evaluation systems to further PATH’s mission. It also highlights two prestigious awards that PATH recently received.

Publication date: December 2009

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health features PATH’s work to improve maternal and newborn health around the world. Articles cover innovative technologies to save newborns, better nutrition for mothers and children, methods to make childbirth safer, and women’s access to more options for family planning.

Publication date: May 2010

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health features a conversation with Chris Elias on the occasion of his ten-year anniversary as PATH’s president and CEO. It also highlights work to pave the way for a total market approach to family planning in Nicaragua and Vietnam, capitalize on the transformation potential of point-of-care tests, address gender’s impact on health, and design better health information systems for developing countries.

Publication date: December 2010

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health features PATH’s work related to vaccines and immunization. Articles cover the development and introduction of a vaccine to eliminate epidemic meningitis in Africa, use of vaccines and other interventions to prevent cervical cancer, transformation of vaccine distribution systems, expansion of access to rotavirus vaccines, and advancements in vaccine technologies.

Publication date: May 2011

Region: Global

Part of series: Directions in Global Health

This issue of Directions in Global Health highlights PATH’s work to reduce the global burden of HIV/AIDS. It describes how PATH strengthens community-based responses; addresses gender norms to reduce HIV risk; integrates services for maximum effectiveness against HIV, tuberculosis, and other health challenges; advances needed technologies; and evaluates project impact. In addition, Dr. Julie Pulerwitz offers her perspective on turning the tide against AIDS.

Publication date: July 2012

Region: Global

Part of series: Directions in Global Health

Part of the Technology Updates series, this fact sheet describes PATH's work on designing the next generation of jet injectors.

Publication date: May 2012

Region: Global

Part of series: Technology Updates

This project Optimize document summarizes a laboratory report on performance testing of four models of domestic refrigerators that are available on the Tunisian market. Project Optimize contracted the tests to demonstrate to the government the importance of prequalification of models according to World Health Organization quality, safety, and standards for the storage of vaccines.

Author: Lloyd J, McCarney S, Ouhichi R

Publication date: October 2012

Region: Africa

This website about PATH’s drug development program provides an overview of the program and its featured projects. See other PATH program websites.

Publication date: 2013

Region: Global

Part of series: PATH's program websites

An exploration of one technique for drying reagents onto a microfluidics card. Reagents needed for immunocapture, lysis, and PCR for pathogen capture can be stored in trehalose or trehalose dextran. Presented at the 1st Distributed Diagnosis and Home Healthcare Conference, April 2, 2006; Arlington, VA.

Author: Ramachandran S, Weigl BH, Gerdes JC, et al

Publication date: April 2006

Region: Global

A pilot clinical study suggests that E6 is an appropriate biomarker for diagnosis of cervical pre-cancer and cancer in a novel oncoprotein-based rapid diagnostic assay for cervical pre-cancer and cancer. Presented at: International Papillomavirus Conference 2009, May 8, 2009; Malmo, Sweden.

Author: Schweizer J, Berard-Bergery M, Bisht A, et al

Publication date: May 2009

Region: Global

This poster describes the AV Avantage HPV E6 Test and the results from a small clinical pilot study. The AV Avantage HPV E6 Test uses high affinity mAb for the specific capture and detection of high-risk HPV-E6 oncoproteins in a lateral flow–based format. Presented at: 26th International Papillomavirus Conference, July 3, 2010; Montreal, Canada.

Author: Berard-Bergery M, Bisht A, Ho M, et al

Publication date: July 2010

Region: Global

Since 2006, PATH has investigated how commercial market forces can help extend access to safe water in developing countries and reduce waterborne disease. Promoting household water treatment and storage products targeted to low-income consumers is a key part of the strategy. This project brief summarizes PATH's work in Malawi working with the US Centers for Disease Control and Prevention to assess the effects of an innovative program that promoted chlorine disinfectants for household water treatment to pregnant women seeking antenatal care.

Author: Kols A, Wood S, Schlanger K

Publication date: September 2012

Region: Africa

Part of series: Safe water briefs

This document is part of a series that describes the serious risk of freezing vaccines and provides tools to reduce freezing in the cold chain. The materials contain current WHO-recommended freeze-prevention strategies targeted toward all levels of storage and transport of vaccines.

Publication date: 2003

Region: Global

Fifteen strains of Escherichia coli from various geographical areas, animal, and soil sources were tested on standard and nonstandard detection assays at temperatures from 23°C to 45°C to test the viability of currently available E. coli tests in low-resource settings. Presented at the American Society for Microbiology Conference, June 1, 2008; Boston, MA.

Author: Allen E, Dillman L, Weigl B

Publication date: June 2008

Region: Global

These fact sheets describe a PATH project focused on expanding prevention options for women.

Publication date: 2002

Region: Global

This poster summarizes PATH's work to pilot tools for water treatment and education about water, sanitation, and hygiene in three primary schools in Western Province, Kenya. The poster was presented at the Water and Health: Where Science Meets Policy conference hosted by the University of North Carolina Water Institute in October 2012.

Author: Forsyth J, Ochola A, Odengo R, et al

Publication date: October 2012

Region: Africa

This report is a synthesis of the project Evaluating HPV Vaccine Delivery Strategies in Vietnam, which aimed to identify appropriate strategies for human papillomavirus (HPV) vaccine delivery in different geographic and socioeconomic conditions. The report summarizes results of both the implementation and research aspects of the project. The document is available as one large file or as four smaller files for easier downloading.

Publication date: December 2010

Region: Asia

This is the final research report on the evaluation of clean delivery kits in Tanzania. The purpose of the study was to determine the impact of a delivery kit intervention on reducing cord infection and puerperal sepsis among newborns and their mothers. Study results indicate that use of the clean delivery kit had a positive effect on reducing both cord infection and puerperal sepsis. The effect of the kit on reducing cord infection was much greater than on puerperal sepsis, but both were significant.

Author: Winani S; Coffey P; Wood S; Mosha F; Chirwa T; Changalucha J

Publication date: 2005

Region: Africa