This overview describes how PATH has developed a low-cost and straightforward technology for protecting aluminum-adjuvanted liquid vaccines from the irreversible damage that results from freezing. Many current vaccines of importance to global health contain an aluminum salt adjuvant or its equivalent (such as aluminum hydroxide, aluminum phosphate, or calcium phosphate) and would benefit from the technology.

Publication date: October 2012

Region: Global

Part of the Technology Updates series, this fact sheet describes PATH's work to develop a rectally administered magnesium sulfate (MgSO4) formulation that could simplify delivery and improve access to MgSO4 treatment in low-resource settings.

Publication date: May 2014

Region: Global

Part of series: Technology Updates

The fourth annual policy report from the Global Health Technologies Coalition outlines actions the United States can take to help reduce deaths, extend lives, and secure healthier futures by supporting research for new health tools.

Publication date: February 2013

Region: North America and Europe

Part of series: GHTC's annual policy reports

It is widely recognized today that ensuring a reliable supply of quality contraceptives is essential to reproductive health programs. The tagline "No product? No program" is known, understood, and embraced by those working to support reproductive health in the developing world. But this was not always the case. This paper tells the story of how what was once seen only as a technical issue became a global movement.

Author: Solo J

Publication date: 2011

Region: Global

This fact sheet from the Global Health Technologies Coalition examines how research for new global health tools can help achieve the Millennium Development Goals.

Publication date: September 2010

Region: Global

Part of the Technology Updates series, this fact sheet provides an overview of PATH’s sanitation strategy, which addresses access and sustainability in four key areas: market approaches, technology and products, financing, and an overall sanitation framework focused on end users in low-resource settings.

Publication date: May 2012

Region: Global

Part of series: Technology Updates

This publication describes the public health potential of multipurpose prevention technologies -- that is, technologies that prevent unintended pregnancy; sexually transmitted infections, including HIV; and/or other reproductive tract infections. While a few such technologies exist, greater collaboration and resources are needed to accelerate research and development efforts and bring new technologies into widespread use.

Author: Holt BY, Kilbourne-Brook M, Cohen J, Burns M

Publication date: May 2010

Region: Global

This fact sheet by the GHTC examines the importance of US government support in global health research and development and how indiscriminate budget cuts will unfairly target global health research and development programs that are effective, save lives, and create jobs.

Publication date: March 2013

Region: North America and Europe

This fact sheet discusses the development and implementation of technologies to improve the health of women and children in poor and remote areas around the world. It provides examples of PATH’s work in this area.

Publication date: September 2011

Region: Global

Part of the Technology Updates series, this fact sheet describes PATH's work to address the health effects of indoor air pollution for the more than one-third of the world's population that uses biomass to cook and heat their homes.

Publication date: August 2013

Region: Global

Part of series: Technology Updates

This second annual policy report from the Global Health Technologies Coalition—a group of almost 40 nonprofit organizations working to increase awareness of the urgent need for vaccines, diagnostics, drugs, microbicides, and other products that save lives in the developing world—outlines some of the steps that will help curb unnecessary deaths, extend lives, and secure healthier futures. Serving as a guide for policymakers, the report documents promising policy actions taken over the past year in the areas of US investments in global health and international development, regulatory pathways to ensure the safety and efficacy of health tools, and incentives and innovative financing mechanisms to spur global health product development. This report offers recommendations for how US policymakers can continue to have a lead in improving health worldwide.

Publication date: 2011

Region: North America and Europe

Part of series: GHTC's annual policy reports

Part of the Technology Updates series, this fact sheet describes PATH's work to assess the value and sustainability of using a simple, affordable spring infusor pump for long-term outpatient administration of antibiotics for the treatment of osteomyelitis in low-resource settings.

Publication date: March 2012

Region: Global

Part of series: Technology Updates

If a highly virulent pandemic strain were to emerge in today’s interconnected world, influenza has the potential to kill millions of people, especially in developing countries with limited to no resources for pandemic planning, preparedness, and outbreak response. PATH's work in developing thermostable influenza vaccines holds promise for extending product shelf life and easing logistics during introduction and rapid deployment to hard-to-reach populations—markedly improving developing-country preparedness and ability to contain the virus at its point of origin. This fact sheet describes our latest research achievements and next steps in product development.

Publication date: September 2013

Region: Global

Postpartum hemorrhage (PPH), or excessive bleeding after childbirth, is the single largest cause of maternal death worldwide. In this poster, created for the 2013 Saving Lives at Birth DevelopmentXChange, PATH proposed to develop heat-stable fast-dissolving oxytocin tablets for sublingual delivery, helping to more easily and effectively prevent and treat PPH in low-resource communities. The small, needle-free tablet format eliminates the risks associated with sharps use and disposal. Its heat stability also reduces the need for expensive cold chain transport and storage.

Publication date: July 2013

Region: Global

Severe preeclampsia and eclampsia (PE/E) are among the leading causes of maternal death and disability worldwide. Magnesium sulfate is the treatment recommended by the World Health Organization, but it remains underutilized due to difficult administration. PATH designed a mobile application for dosing and dilution of magnesium sulfate to address the challenges of correctly calculating magnesium sulfate dosage given multiple concentrations and a complex dosing regimen.

Publication date: May 2014

Region: Global

This document summarizes PATH’s work in Indonesia to sustain best practices among health workers in project provinces through a supportive supervision program.

Publication date: April 2008

Region: Global

The third annual policy report from the Global Health Technologies Coalition outlines actions the United States can take to help reduce deaths, extend lives, and secure healthier futures by supporting research for new health tools.

Publication date: 2012

Region: North America and Europe

Part of series: GHTC's annual policy reports

This fact sheet highlights PATH's health technology solutions from the past 30 years.

Publication date: April 2014

Region: Global

This website about PATH’s Technology Solutions program provides an overview of the program and its featured projects. See other PATH program websites.

Publication date: 2014

Region: Global

Part of series: Program websites

Part of the Technology Updates series, this fact sheet describes the Ultra Rice project at PATH.

Publication date: August 2013

Region: Global

Part of series: Technology Updates