Disposable-syringe jet injector components.

PATH has conducted user assessments of jet injectors, providing feedback to device manufacturers.

Disposable-syringe jet injectors (DSJIs) operate without the use of needles. They deliver vaccines or medications by generating a pressurized liquid stream that penetrates through the skin and delivers injections to intradermal, subcutaneous, or intramuscular tissue. DSJIs are the only available needle-free technology that can deliver all injectable vaccines used in developing-country programs at all depths of delivery.

PATH has worked with several jet injector companies over the years to advance “second-generation” or disposable-syringe jet injectors. Early-model jet injectors were introduced to the immunization scene in the 1940s and were used to give millions of injections—even helping to eradicate smallpox. These jet injectors operated with a reusable nozzle, and they fell out of favor in the 1990s due to concerns of cross-contamination.

New injectors circumvent these risks by using disposable needle-free syringes—each containing a single dose of vaccine—that prevent the transmission of infection from one person to the next. The autodisable syringe is discarded after each use, while the simple design ensures safe administration by health care professionals.

DSJIs improve injection safety by eliminating the risk of needle and syringe reuse, preventing needlestick injuries, and reducing the overall burden of sharps waste.

Photo: PATH/Scott Areman.